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胸椎原发性哑铃形硬膜外黏液样脂肪肉瘤:1例报告并文献复习

Primary dumbbell-shaped epidural myxoid liposarcoma of the thoracic spine: A case report and review of the literature.

作者信息

Kaneuchi Yoichi, Hakozaki Michiyuki, Yamada Hitoshi, Tajino Takahiro, Watanabe Kazuyuki, Otani Koji, Hojo Hiroshi, Hasegawa Tadashi, Konno Shinichi

机构信息

Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan.

Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima 960-1295, Japan; Division of Orthopaedic Surgery, Southern Tohoku Fukushima Hospital, Fukushima 960-2102, Japan.

出版信息

Oncol Lett. 2016 Feb;11(2):1421-1424. doi: 10.3892/ol.2016.4089. Epub 2016 Jan 8.

Abstract

Myxoid liposarcoma frequently occurs in the deep soft tissue of the extremities, particularly in the thigh. The present study describes an extremely rare case of primary dumbbell-shaped epidural myxoid liposarcoma of the thoracic spine occurring in a 22-year-old woman. Although preoperative magnetic resonance imaging findings were thought to be compatible with schwannoma, the pathological diagnosis of the resected tumor was myxoid liposarcoma. The patient underwent three courses of adjuvant chemotherapy with doxorubicin and ifosfamide, and exhibited no symptoms or signs of local recurrence or metastasis for 18 months post surgery. The present case suggests that, when radiologically diagnosing spinal epidural tumors, clinicians should consider the possibility of myxoid liposarcoma.

摘要

黏液样脂肪肉瘤常发生于四肢深部软组织,尤其是大腿。本研究描述了一例极为罕见的原发性哑铃形胸椎硬膜外黏液样脂肪肉瘤,发生于一名22岁女性。尽管术前磁共振成像结果被认为与神经鞘瘤相符,但切除肿瘤的病理诊断为黏液样脂肪肉瘤。该患者接受了三个疗程的阿霉素和异环磷酰胺辅助化疗,术后18个月未出现局部复发或转移的症状或体征。本病例提示,在对脊柱硬膜外肿瘤进行放射学诊断时,临床医生应考虑黏液样脂肪肉瘤的可能性。

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