Xing Yu-Fei, Xu Yue-Hua, Shi Min-Hua, Lian Yi-Xin
Department of Respiratory Medicine, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
J Thorac Dis. 2016 Jan;8(1):E69-74. doi: 10.3978/j.issn.2072-1439.2016.01.19.
Recently, many researchers paid more attentions to the association between air pollution and respiratory system disease. In the past few years, levels of smog have increased throughout China resulting in the deterioration of air quality, raising worldwide concerns. PM2.5 (particles less than 2.5 micrometers in diameter) can penetrate deeply into the lung, irritate and corrode the alveolar wall, and consequently impair lung function. Hence it is important to investigate the impact of PM2.5 on the respiratory system and then to help China combat the current air pollution problems. In this review, we will discuss PM2.5 damage on human respiratory system from epidemiological, experimental and mechanism studies. At last, we recommend to the population to limit exposure to air pollution and call to the authorities to create an index of pollution related to health.
最近，许多研究人员更加关注空气污染与呼吸系统疾病之间的关联。在过去几年中，中国各地的雾霾水平不断上升，导致空气质量恶化，引起了全球关注。细颗粒物（直径小于2.5微米的颗粒物）可深入肺部，刺激并侵蚀肺泡壁，进而损害肺功能。因此，研究细颗粒物对呼吸系统的影响，对于帮助中国应对当前的空气污染问题具有重要意义。在这篇综述中，我们将从流行病学、实验和机制研究等方面探讨细颗粒物对人类呼吸系统的损害。最后，我们建议公众限制暴露于空气污染环境中，并呼吁当局制定与健康相关的污染指数。
