Siddiq Y K
J Med Assoc Ga. 1989 Nov;78(11):775-6.
Evidence now exists that maintaining normal maternal plasma glucose in the diabetic mother results in an infant mortality risk equal to that in the general population and may reduce the late fetal complications of maternal diabetes: macrosomia and perinatal hypoglycemia. Careful attention to diet, home glucose monitoring, multiple insulin injections, and frequent dose adjustments are often required to achieve this goal. Since organ development occurs within the first few weeks after conception, pregnancy planning and optimization of diabetes management prior to pregnancy is critical to good outcome in diabetic women eager to begin a family.
现有证据表明,维持糖尿病母亲的母体血浆葡萄糖正常,可使婴儿死亡率风险与普通人群相当,并可能减少母体糖尿病的晚期胎儿并发症:巨大儿和围产期低血糖。为实现这一目标,通常需要密切关注饮食、家庭血糖监测、多次胰岛素注射以及频繁调整剂量。由于器官发育在受孕后的头几周内发生,对于渴望生育的糖尿病女性而言,孕前规划和优化糖尿病管理对于取得良好结局至关重要。