Matsumura Yoko, Ito Toshihiro, Yano Hisakazu, Kita Eiji, Mikasa Keiichi, Okada Masatoshi, Furutani Azusa, Murono Yuka, Shibata Mitsuru, Nishii Yasue, Kayano Shin-Ichi
Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan; Department of Immunology, Nara Medical University, 840 Shijo-cho, Kashihara-City, Nara 634-8521, Japan.
Department of Immunology, Nara Medical University, 840 Shijo-cho, Kashihara-City, Nara 634-8521, Japan.
Food Chem. 2016 Jul 1;202:99-103. doi: 10.1016/j.foodchem.2016.01.112. Epub 2016 Jan 28.
Dried fruits of persimmon (Diospyros kaki Thunb.) are a traditional food in Japan and contain large quantities of tannins. In this study, we investigated the in vitro and in vivo antioxidant potentials of non-extractable fractions from dried persimmons. Hydrolysed non-extractable fractions showed the highest antioxidant activities in vitro. In subsequent experiments, the plasma oxygen radical absorbance capacity (ORAC) values in rats supplemented with a 5% non-extractable fraction were approximately 1.5times higher than those in control rats after 1week in vivo. Furthermore, using an in vitro model of the gastrointestinal tract, the ORAC values of the non-extractable fraction were significantly increased with colonic fermentation in the large bowel stage. These data indicate that non-extractable fractions may possess significant antioxidant potential in vitro and in vivo.
柿子（Diospyros kaki Thunb.）的干果是日本的传统食品，含有大量单宁。在本研究中，我们调查了柿子干中不可提取部分的体外和体内抗氧化潜力。水解后的不可提取部分在体外表现出最高的抗氧化活性。在随后的实验中，补充5%不可提取部分的大鼠在体内1周后，其血浆氧自由基吸收能力（ORAC）值比对照大鼠高出约1.5倍。此外，使用胃肠道体外模型，不可提取部分的ORAC值在大肠阶段随着结肠发酵而显著增加。这些数据表明，不可提取部分在体外和体内可能具有显著的抗氧化潜力。
