Ernst Sinja Alexandra, Schmitz Roma, Thamm Michael, Ellert Ute
Leibniz Institute for Prevention Research and Epidemiology-BIPS, Achterstraße 30, 28359 Bremen, Germany.
Robert Koch Institute, General-Pape-Str. 62-66, 12101 Berlin, Germany.
Int J Environ Res Public Health. 2016 Feb 26;13(3):265. doi: 10.3390/ijerph13030265.
In industrialized countries atopic diseases have been reported to be less likely in children and adolescents with a migrant background compared to non-migrants. This paper aimed at both examining and comparing prevalence of asthma, allergic rhinoconjunctivitis and atopic dermatitis and allergic sensitization to specific IgE antibodies in children and adolescents with and without a migrant background. Using data of the population-based German Health Interview and Examination Survey for children and adolescents (KiGGS;n = 17,450; 0-17 years), lifetime and 12-month prevalence of atopic diseases and point prevalence of 20 common allergic sensitizations were investigated among migrants compared to non-migrants. Multiple regression models were used to estimate the association of atopic disease and allergic sensitization with migrant background. In multivariate analyses with substantial adjustment we found atopic dermatitis about one-third less often (OR 0.73, 0.57-0.93) in participants with a two-sided migrant background. Statistically significant associations between allergic sensitizations and a two-sided migrant background remained for birch (OR 0.73, 0.58-0.90), soybean (OR 0.72, 0.54-0.96), peanut (OR 0.69, 0.53-0.90), rice (OR 0.64, 0.48-0.87), potato (OR 0.64, 0.48-0.85), and horse dander (OR 0.58, 0.40-0.85). Environmental factors and living conditions might be responsible for the observed differences.
据报道，在工业化国家，与非移民儿童和青少年相比，有移民背景的儿童和青少年患特应性疾病的可能性较小。本文旨在研究和比较有和没有移民背景的儿童和青少年中哮喘、过敏性鼻结膜炎、特应性皮炎的患病率以及对特异性IgE抗体的过敏致敏情况。利用基于人群的德国儿童和青少年健康访谈与检查调查（KiGGS；n = 17450；0 - 17岁）的数据，调查了移民与非移民中特应性疾病的终生患病率和12个月患病率以及20种常见过敏致敏的点患病率。使用多元回归模型估计特应性疾病和过敏致敏与移民背景之间的关联。在进行大量调整的多变量分析中，我们发现具有双向移民背景的参与者患特应性皮炎的几率低约三分之一（OR 0.73，0.57 - 0.93）。对于桦树（OR 0.73，0.58 - 0.90）、大豆（OR 0.72，0.54 - 0.96）、花生（OR 0.69，0.53 - 0.90）、大米（OR 0.64，0.48 - 0.87）、土豆（OR 0.64，0.48 - 0.85）和马皮屑（OR 0.58，0.40 - 0.85），过敏致敏与双向移民背景之间存在统计学上的显著关联。环境因素和生活条件可能是观察到的差异的原因。
