草药替代品（余甘子、番石榴）、MTAD和2.5%次氯酸钠对粪肠球菌的抗菌效果比较：一项体外研究。
Comparative antimicrobial efficacy of herbal alternatives (Emblica officinalis, Psidium guajava), MTAD, and 2.5% sodium hypochlorite against Enterococcus faecalis: An in vitro study.
作者信息
Dubey Sandeep
机构信息
Senior Lecturer, Conservative Dentistry and Endodontics, College of Dental Sciences and Hospital, Indore, Madhya Pradesh 453331, India.
出版信息
J Oral Biol Craniofac Res. 2016 Jan-Apr;6(1):45-8. doi: 10.1016/j.jobcr.2015.12.010. Epub 2016 Jan 20.
AIM
The objective of this study was to evaluate the antimicrobial efficacy of herbal alternatives (Emblica officinalis, Psidium guajava), BioPure MTAD, and 2.5% sodium hypochlorite against Enterococcus faecalis.
MATERIALS AND METHOD
The testing of the antimicrobial efficacy of selected medicaments against E. faecalis was done by the agar disk-diffusion method. Whatman paper discs of 6 mm diameter were prepared and soaked with the test solution. These discs were then placed onto the previously seeded agar Petri plates. Later, these plates were incubated for 48 h at 37 °C under the appropriate gaseous conditions in a CO2 incubator. A zone of inhibition was recorded in millimeter for each plate and the results were analyzed statistically.
RESULT
MTAD was found to be superior in its antibacterial abilities against E. faecalis compared with the other irrigants used. All the other tested irrigants showed significant zone of inhibition.
CONCLUSIONS
BioPure MTAD offers better antibacterial efficacy than NaOCl. E. officinalis and P. guajava are effective antibacterial agents against E. faecalis and can be used to reduce root canal microflora and root canal failures.
目的
本研究的目的是评估草药替代品（余甘子、番石榴）、BioPure MTAD和2.5%次氯酸钠对粪肠球菌的抗菌效果。
材料与方法
采用琼脂纸片扩散法检测所选药物对粪肠球菌的抗菌效果。制备直径6毫米的Whatman纸片，并用测试溶液浸泡。然后将这些纸片置于预先接种了菌的琼脂平板上。之后，将这些平板在二氧化碳培养箱中于37℃、适当的气体条件下孵育48小时。记录每个平板的抑菌圈大小（以毫米为单位），并对结果进行统计学分析。
结果
与其他冲洗剂相比，发现MTAD对粪肠球菌的抗菌能力更强。所有其他测试的冲洗剂均显示出明显的抑菌圈。
结论
BioPure MTAD比NaOCl具有更好的抗菌效果。余甘子和番石榴是对粪肠球菌有效的抗菌剂，可用于减少根管微生物群和根管治疗失败。
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