在眶额叶和腹内侧前额叶皮质内，为学习和决策对相关信息进行优先级排序。
Prioritising the relevant information for learning and decision making within orbital and ventromedial prefrontal cortex.
作者信息
Walton Mark E, Chau Bolton K H, Kennerley Steven W
机构信息
Department of Experimental Psychology, University of Oxford, Oxford, UK.
Institute of Neurology, UCL, London, UK.
出版信息
Curr Opin Behav Sci. 2015 Feb 1;1:78-85. doi: 10.1016/j.cobeha.2014.10.005.
Abstract
Our environment and internal states are frequently complex, ambiguous and dynamic, meaning we need to have selection mechanisms to ensure we are basing our decisions on currently relevant information. Here, we review evidence that orbitofrontal (OFC) and ventromedial prefrontal cortex (VMPFC) play conserved, critical but distinct roles in this process. While OFC may use specific sensory associations to enhance task-relevant information, particularly in the context of learning, VMPFC plays a role in ensuring irrelevant information does not impinge on the decision in hand.
摘要
我们的环境和内部状态常常复杂、模糊且动态变化，这意味着我们需要具备选择机制，以确保我们的决策基于当前相关信息。在此，我们回顾相关证据，表明眶额皮质（OFC）和腹内侧前额叶皮质（VMPFC）在这一过程中发挥着保守、关键但又不同的作用。虽然眶额皮质可能利用特定的感觉关联来增强与任务相关的信息，尤其是在学习情境中，但腹内侧前额叶皮质在确保无关信息不会影响手头决策方面发挥着作用。
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1
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Elife. 2014 Jul 18;3:e02653. doi: 10.7554/eLife.02653.
2
Orbitofrontal neurons infer the value and identity of predicted outcomes.眶额神经元推断预测结果的价值和特征。
Nat Commun. 2014 Jun 4;5:3926. doi: 10.1038/ncomms4926.
3
Reward value comparison via mutual inhibition in ventromedial prefrontal cortex.腹内侧前额叶皮层通过相互抑制进行奖励值比较。
Neuron. 2014 Jun 18;82(6):1357-66. doi: 10.1016/j.neuron.2014.04.032. Epub 2014 May 29.
4
Distinguishing informational from value-related encoding of rewarding and punishing outcomes in the human brain.区分人类大脑中奖励和惩罚结果的信息编码与价值相关编码。
Eur J Neurosci. 2014 Jun;39(11):2014-26. doi: 10.1111/ejn.12625. Epub 2014 May 24.
5
Disentangling neural representations of value and salience in the human brain.解析人类大脑中价值和显著度的神经表示。
Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):5000-5. doi: 10.1073/pnas.1320189111. Epub 2014 Mar 17.
6
A neural mechanism underlying failure of optimal choice with multiple alternatives.多选项最优选择失败的神经机制。
Nat Neurosci. 2014 Mar;17(3):463-70. doi: 10.1038/nn.3649. Epub 2014 Feb 9.
7
Orbitofrontal cortex as a cognitive map of task space.眶额皮质作为任务空间的认知图。
Neuron. 2014 Jan 22;81(2):267-279. doi: 10.1016/j.neuron.2013.11.005.
8
Effects of amygdala lesions on reward-value coding in orbital and medial prefrontal cortex.杏仁核损伤对眶额皮质和内侧前额叶皮质中奖赏值编码的影响。
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9
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10
Single-neuron mechanisms underlying cost-benefit analysis in frontal cortex.前额叶皮层中成本效益分析的单神经元机制。
J Neurosci. 2013 Oct 30;33(44):17385-97. doi: 10.1523/JNEUROSCI.2221-13.2013.
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