Walton Mark E, Chau Bolton K H, Kennerley Steven W
Department of Experimental Psychology, University of Oxford, Oxford, UK.
Institute of Neurology, UCL, London, UK.
Curr Opin Behav Sci. 2015 Feb 1;1:78-85. doi: 10.1016/j.cobeha.2014.10.005.
Our environment and internal states are frequently complex, ambiguous and dynamic, meaning we need to have selection mechanisms to ensure we are basing our decisions on currently relevant information. Here, we review evidence that orbitofrontal (OFC) and ventromedial prefrontal cortex (VMPFC) play conserved, critical but distinct roles in this process. While OFC may use specific sensory associations to enhance task-relevant information, particularly in the context of learning, VMPFC plays a role in ensuring irrelevant information does not impinge on the decision in hand.
我们的环境和内部状态常常复杂、模糊且动态变化，这意味着我们需要具备选择机制，以确保我们的决策基于当前相关信息。在此，我们回顾相关证据，表明眶额皮质（OFC）和腹内侧前额叶皮质（VMPFC）在这一过程中发挥着保守、关键但又不同的作用。虽然眶额皮质可能利用特定的感觉关联来增强与任务相关的信息，尤其是在学习情境中，但腹内侧前额叶皮质在确保无关信息不会影响手头决策方面发挥着作用。
