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巴伐利亚学龄前儿童家长报告过敏患病率未见进一步增加:三项横断面研究的结果。

No further increase in the parent reported prevalence of allergies in Bavarian preschool children: Results from three cross-sectional studies.

机构信息

Department of Occupational and Environmental Epidemiology, Bavarian Health and Food Safety Authority, Pfarrstr. 3, 80538, Munich, Germany.

Department of Occupational and Environmental Epidemiology, Bavarian Health and Food Safety Authority, Pfarrstr. 3, 80538, Munich, Germany.

出版信息

Int J Hyg Environ Health. 2016 Jul;219(4-5):343-8. doi: 10.1016/j.ijheh.2016.02.001. Epub 2016 Feb 15.

DOI:10.1016/j.ijheh.2016.02.001
PMID:26944211
Abstract

BACKGROUND

After three decades of an increase in the prevalence of asthma and allergies, new findings show a plateau in the prevalence of industrialized nations. The objective of this study was to determine whether there was a change in the parent reported prevalence of asthma and allergies among Bavarian preschool children since 2004.

METHODS

A parent questionnaire was administered as part of the Bavarian school entrance examination in three cross-sectional studies from 2004/2005, 2006/2007 and 2012/2013. The questionnaire included items on allergy testing history, identified allergens, symptoms (e.g. wheezing, itchy eyes, rash), medically diagnosed asthma, hay fever and atopic dermatitis. Logistic regression was performed to observe time patterns and adjust for risk factors.

RESULTS

Data were available for 6350 (2004/2005), 6483 (2006/2007) and 5052 (2012/2013) individuals. Symptoms and diseases were more frequent in boys, except for allergies which affect the skin. From 2004 to 2012 the parent reported prevalence of asthma (2.6% to 2.8%), hay fever (4.7% to 4.0%) and atopic dermatitis (12.4% to 11.1%) either remained quite stable or decreased not significantly.

CONCLUSIONS

Results from these three cross-sectional surveys of parent reports suggest that the parent reported prevalences of asthma and allergies are quite stable with small fluctuations since 2004 for Bavarian preschool children. Future research is needed to determine if this trend will continue.

摘要

背景

经过三十年哮喘和过敏发病率的上升,新的研究结果显示工业化国家的发病率已趋于平稳。本研究旨在确定自 2004 年以来巴伐利亚学龄前儿童父母报告的哮喘和过敏发病率是否发生变化。

方法

在 2004/2005、2006/2007 和 2012/2013 年的三项横断面研究中,通过父母问卷作为巴伐利亚入学考试的一部分进行调查。问卷包括过敏测试史、过敏原、症状(如喘息、眼痒、皮疹)、医学诊断的哮喘、花粉热和特应性皮炎。采用逻辑回归观察时间模式并调整危险因素。

结果

共有 6350 人(2004/2005 年)、6483 人(2006/2007 年)和 5052 人(2012/2013 年)的数据可用。除了影响皮肤的过敏症状外,男孩的症状和疾病更为常见。2004 年至 2012 年,父母报告的哮喘(2.6%至 2.8%)、花粉热(4.7%至 4.0%)和特应性皮炎(12.4%至 11.1%)的发病率保持相当稳定或略有下降。

结论

这三项父母报告的横断面调查结果表明,自 2004 年以来,巴伐利亚学龄前儿童的哮喘和过敏父母报告发病率相当稳定,略有波动。需要进一步研究以确定这一趋势是否会持续。

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