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德国儿童和青少年的过敏性疾病。横断面KiGGS第二轮研究结果及趋势

Allergic diseases in children and adolescents in Germany. Results of the cross-sectional KiGGS Wave 2 study and trends.

作者信息

Thamm Roma, Poethko-Müller Christina, Hüther Antje, Thamm Michael

机构信息

Robert Koch Institute, Berlin, Department of Epidemiology and Health Monitoring.

出版信息

J Health Monit. 2018 Sep 19;3(3):3-16. doi: 10.17886/RKI-GBE-2018-082. eCollection 2018 Sep.

Abstract

Allergic diseases are among the most common health issues children and adolescents face. Allergic reactions occur when the immune system becomes allergically sensitised and are detected by measuring levels of specific immunoglobulin E antibodies (IgE antibodies) in the blood. This article discusses the prevalences of bronchial asthma, hay fever, atopic dermatitis and allergic contact dermatitis for 0- to 17-year-olds, as well as the prevalence of allergic sensitisation to a mix of frequent inhalant allergens (SX1) among 3- to 17-year-olds based on data from the second wave of the German Health Interview and Examination Survey for Children and Adolescents (KiGGS Wave 2, 2014-2017). 12-month prevalence trends between KiGGS Wave 2 and the KiGGS baseline study (2003-2006) are shown according to gender and age group. There were no significant changes in the 12-month prevalence of hay fever (8.8%) atopic dermatitis (7.0%) and bronchial asthma (3.5%) compared to the KiGGS baseline study, which indicates a stabilisation at a high level. More than one in six children (16.1%) currently suffer from at least one of these three diseases. 37.1% of 3- to 17-year-olds are sensitised to the multiple allergen mix SX1. Similar to the development of disease prevalence, SX1 sensitisation too has remained stable at a high level over the course of the past ten years.

摘要

过敏性疾病是儿童和青少年面临的最常见健康问题之一。当免疫系统发生过敏致敏时就会发生过敏反应,可通过检测血液中特定免疫球蛋白E抗体(IgE抗体)的水平来发现。本文基于德国儿童和青少年健康访谈与检查调查第二轮(KiGGS Wave 2,2014 - 2017年)的数据,讨论了0至17岁儿童支气管哮喘、花粉症、特应性皮炎和过敏性接触性皮炎的患病率,以及3至17岁儿童对多种常见吸入性过敏原混合物(SX1)的过敏致敏率。根据性别和年龄组展示了KiGGS Wave 2与KiGGS基线研究(2003 - 2006年)之间的12个月患病率趋势。与KiGGS基线研究相比,花粉症(8.8%)、特应性皮炎(7.0%)和支气管哮喘(3.5%)的12个月患病率没有显著变化,这表明患病率在高水平上趋于稳定。超过六分之一的儿童(16.1%)目前患有这三种疾病中的至少一种。3至17岁儿童中有37.1%对多种过敏原混合物SX1过敏致敏。与疾病患病率的发展情况类似,在过去十年中,对SX1的过敏致敏率也一直稳定在较高水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e91/8848849/d326ca3754d7/johm-3-3-03-g001.jpg

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