Youn Inyoung, Choi SeonHyeong, Kook Shin Ho, Choi Yoon Jung
Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea .
J Korean Med Sci. 2016 Mar;31(3):457-62. doi: 10.3346/jkms.2016.31.3.457. Epub 2016 Feb 23.
The purpose was to present mean breast density of Korean women according to age using fully automated volumetric assessment. This study included 5,967 screening normal or benign mammograms (mean age, 46.2 ± 9.7; range, 30-89 years), from cancer-screening program. We evaluated mean fibroglandular tissue volume, breast tissue volume, volumetric breast density (VBD), and the results were 53.7 ± 30.8 cm(3), 383.8 ± 205.2 cm(3), and 15.8% ± 7.3%. The frequency of dense breasts and mean VBD by age group were 94.3% and 19.1% ± 6.7% for the 30s (n = 1,484), 91.4% and 17.2% ± 6.8% for the 40s (n = 2,706), 72.2% and 12.4% ± 6.2% for the 50s (n = 1,138), 44.0% and 8.6% ± 4.3% for the 60s (n = 89), 39.1% and 8.0% ± 3.8% for the 70s (n = 138), and 39.1% and 8.0% ± 3.5% for the 80s (n = 12). The frequency of dense breasts was higher in younger women (n = 4,313, 92.3%) than older women (n = 1,654, 59.8%). Mean VBD decreased with aging or menopause, and was about 16% for 46-year-old-Korean women, much higher than in other countries. The proportion of dense breasts sharply decreases in Korean women between 40 and 69 years of age.
目的是通过全自动容积评估呈现韩国女性按年龄划分的平均乳腺密度。本研究纳入了来自癌症筛查项目的5967例筛查结果为正常或良性的乳房X光片（平均年龄46.2±9.7岁；范围30 - 89岁）。我们评估了平均纤维腺体组织体积、乳房组织体积、容积性乳腺密度（VBD），结果分别为53.7±30.8立方厘米、383.8±205.2立方厘米和15.8%±7.3%。各年龄组致密乳腺的频率和平均VBD分别为：30多岁组（n = 1484）为94.3%和19.1%±6.7%，40多岁组（n = 2706）为91.4%和17.2%±6.8%，50多岁组（n = 1138）为72.2%和12.4%±6.2%，60多岁组（n = 89）为44.0%和8.6%±4.3%，70多岁组（n = 138）为39.1%和8.0%±3.8%，80多岁组（n = 12）为39.1%和8.0%±3.5%。年轻女性（n = 4313，92.3%）中致密乳腺的频率高于年长女性（n = 1654，59.8%）。平均VBD随年龄增长或绝经而降低，46岁的韩国女性平均VBD约为16%，远高于其他国家。韩国女性在40至69岁之间致密乳腺的比例急剧下降。
