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超声引导下腹直肌鞘阻滞和腹横肌平面阻滞在上腹部手术围手术期镇痛中的应用:一项随机对照研究。

Ultrasound-guided rectus sheath and transversus abdominis plane blocks for perioperative analgesia in upper abdominal surgery: A randomized controlled study.

作者信息

Abdelsalam Khaled, Mohamdin O W

机构信息

Department of Anesthesia, Faculty of Medicine, Ain Shams University, Cairo, Egypt; Department of Anesthesia, Faculty of Medicine, King Fahd Specialist Hospital, Dammam, Saudi Arabia.

Department of Anesthesia, Faculty of Medicine, King Fahd Specialist Hospital, Dammam, Saudi Arabia.

出版信息

Saudi J Anaesth. 2016 Jan-Mar;10(1):25-8. doi: 10.4103/1658-354X.169470.

Abstract

BACKGROUND

Regional anesthetic techniques can be used to alleviate postoperative pain in patients undergoing major upper abdominal surgery. Our aim was to evaluate the efficacy of bilateral ultrasound (US)-guided rectus sheath (RS) and transversus abdominis plane (TAP) blocks for better perioperative analgesia.

PATIENTS AND METHODS

It is a prospective, observer-blinded, randomized clinical study. 40 eligible patients undergoing elective liver resection or Whipple procedure were included. All patients received a standardized anesthetic technique. Group 1 (n = 20) received preincisional US-guided bilateral RS and TAP blocks using 20 ml volume of bupivacaine 0.25% for each, and group 2 (n = 20) received local wound infiltration at end of surgery with 40 ml of bupivacaine 0.25%. A standardized postoperative analgesic regimen composed of intravenous paracetamol and a morphine patient-controlled analgesia (PCA). The use of intraoperative fentanyl and recovery room morphine boluses, PCA-administered morphine, pain scores as well as number of patients' experienced postoperative nausea and vomiting in the ward at 6 and 24 h were recorded.

RESULTS

Group 1 patients received a significantly lower cumulative intraoperative fentanyl, significantly lesser boluses of morphine in postanesthesia care unit, as well, significantly lower cumulative 24 h postoperative morphine dosage than the group 2 patients. Pain visual analog scale scores were significantly lower at both 6 and 24 h postoperatively in TAP group when compared with the no-TAP group. There were no complications related to the TAP block procedures. No signs or symptoms of local anesthetic systemic toxicity were detected.

CONCLUSION

The combination of bilateral US-guided RS and TAP blocks provides excellent perioperative analgesia for major upper abdominal surgery.

摘要

背景

区域麻醉技术可用于缓解接受上腹部大手术患者的术后疼痛。我们的目的是评估双侧超声引导下腹直肌鞘(RS)阻滞和腹横肌平面(TAP)阻滞在改善围手术期镇痛方面的效果。

患者与方法

这是一项前瞻性、观察者盲法、随机对照临床研究。纳入40例接受择期肝切除术或惠普尔手术的符合条件患者。所有患者均接受标准化麻醉技术。第1组(n = 20)在切开前接受双侧超声引导下RS和TAP阻滞,每侧使用20 ml 0.25%布比卡因,第2组(n = 20)在手术结束时接受40 ml 0.25%布比卡因局部伤口浸润。采用由静脉注射对乙酰氨基酚和吗啡患者自控镇痛(PCA)组成的标准化术后镇痛方案。记录术中芬太尼的使用情况、恢复室吗啡推注量、PCA使用的吗啡量、疼痛评分以及患者在病房6小时和24小时时术后恶心呕吐的发生例数。

结果

与第2组患者相比,第1组患者术中芬太尼累积用量显著更低,麻醉后护理单元吗啡推注量显著更少,术后24小时吗啡累积用量也显著更低。与非TAP组相比,TAP组术后6小时和24小时的疼痛视觉模拟量表评分均显著更低。未发生与TAP阻滞操作相关的并发症。未检测到局部麻醉药全身毒性的体征或症状。

结论

双侧超声引导下RS和TAP阻滞联合应用可为上腹部大手术提供出色的围手术期镇痛效果。

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