一名因溃疡性结肠炎长期服用柳氮磺胺吡啶的患者发生卵巢淋巴瘤。
Ovarian lymphoma in a patient on long-term sulfasalazine for ulcerative colitis.
作者信息
Kaluarachchi Athula, Bambaranda B G I K, Jayawardena U G, De Silva H J, Matwani S M A, Rameshkumar U
机构信息
Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Department of Medicine, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
出版信息
J Family Med Prim Care. 2020 Jan 28;9(1):442-444. doi: 10.4103/jfmpc.jfmpc_886_19. eCollection 2020 Jan.
We report a case of ovarian lymphoma in a 59 year old woman with ulcerative colitis for over 20 years. She presented with intermittent high fever and right sided abdominal pain for 3 weeks. An ultrasound scan and CT scan revealed a right adnexal mass measuring 71 X 54 mm which was well defined with a thick wall and internal septations and enlarged pelvic and para aortic lymph nodes. The patient underwent bilateral salpingo oophorectomy and omentectomy. Histology confirmed a diffuse large B cell Non Hodgkin's lymphoma and she was referred for chemotherapy. After 6 cycles of chemotherapy she showed a good response. Lymphoma of the gastrointestinal tract arising in a background of ulcerative colitis has been known to occur, ovarian lymphoma with a background of ulcerative colitis has not been reported.
我们报告一例59岁患有溃疡性结肠炎20多年的女性卵巢淋巴瘤病例。她出现间歇性高热和右侧腹痛3周。超声扫描和CT扫描显示右侧附件区有一个大小为71×54mm的肿块,边界清晰,壁厚且有内部间隔,盆腔和腹主动脉旁淋巴结肿大。患者接受了双侧输卵管卵巢切除术和大网膜切除术。组织学证实为弥漫性大B细胞非霍奇金淋巴瘤,她被转诊接受化疗。6个周期的化疗后她显示出良好的反应。已知在溃疡性结肠炎背景下会发生胃肠道淋巴瘤,但有溃疡性结肠炎背景的卵巢淋巴瘤尚未见报道。
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