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皮肤胶原性血管病:一例罕见病例报告。

Cutaneous collagenous vasculopathy: A rare case report.

作者信息

Rambhia Kinjal Deepak, Hadawale Snehal D, Khopkar Uday S

机构信息

Department of Dermatology, Seth GS Medical College, KEM Hospital, Mumbai, Maharashtra, India.

Consultant Dermatologist New Snehadeep Skin and Eye Hospital, Mumbai, Maharashtra, India.

出版信息

Indian Dermatol Online J. 2016 Jan-Feb;7(1):40-2. doi: 10.4103/2229-5178.174327.

Abstract

Cutaneous collagenous vasculopathy (CCV) is a distinct, rare, and underdiagnosed condition. We report a case of CCV in a 50-year-old woman presenting as asymptomatic, erythematous to hyperpigmented nonblanchable macules over both the lower extremities. The clinical differential diagnosis of the lesions was pigmented purpuric dermatoses (Schamberg's purpura) and cutaneous small vessel vasculitis. Histology of the lesions revealed dilated superficial dermal vessels with abundant pink hyaline material in the vessel wall, which stained with periodic acid Schiff stain. The patient was diagnosed as CCV. This condition remains largely underdiagnosed and is commonly mistaken for pigmented purpuric dermatosis or generalized essential telangiectasia. Emphasis on the differentiation of CCV from its clinical and histological mimicks is made.

摘要

皮肤胶原性血管病(CCV)是一种独特、罕见且易被漏诊的疾病。我们报告了一例50岁女性的CCV病例,其表现为双下肢无症状的、从红斑到色素沉着的不可压褪色斑疹。这些皮损的临床鉴别诊断为色素性紫癜性皮病(尚伯格紫癜)和皮肤小血管炎。皮损组织学检查显示真皮浅层血管扩张,血管壁有丰富的粉红色透明物质,经高碘酸希夫染色呈阳性。该患者被诊断为CCV。这种疾病在很大程度上仍未得到充分诊断,常被误诊为色素性紫癜性皮病或泛发性特发性毛细血管扩张症。本文着重强调了CCV与其临床及组织学上相似疾病的鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5631/4763579/73da5944ee41/IDOJ-7-40-g001.jpg

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