Ma Guangming, He Taiping, Yu Yong, Duan Haifeng, Yang Chuangbo
Affiliated Hospital of Shannxi University of Traditional Chinese Medicine Radiology Dept, Xianyang City, Shaanxi, China.
PLoS One. 2016 Mar 11;11(3):e0150985. doi: 10.1371/journal.pone.0150985. eCollection 2016.
To evaluate the clinical value of using monochromatic images in spectral CT pulmonary angiography to improve image quality of bronchial arteries.
We retrospectively analyzed the chest CT images of 38 patients who underwent contrast-enhanced spectral CT. These images included a set of 140kVp polychromatic images and the default 70keV monochromatic images. Using the standard Gemstone Spectral Imaging (GSI) viewer on an advanced workstation (AW4.6,GE Healthcare), an optimal energy level (in keV) for obtaining the best contrast-to-noise ratio (CNR) for the artery could be automatically obtained. The signal-to-noise ratio (SNR), CNR and objective image quality score (1-5) for these 3 image sets (140kVp, 70keV and optimal energy level) were obtained and, statistically compared. The image quality score consistency between the two observers was also evaluated using Kappa test.
The optimal energy levels for obtaining the best CNR were 62.58±2.74keV.SNR and CNR from the 140kVp polychromatic, 70keV and optimal keV monochromatic images were (16.44±5.85, 13.24±5.52), (20.79±7.45, 16.69±6.27) and (24.9±9.91, 20.53±8.46), respectively. The corresponding subjective image quality scores were 1.97±0.82, 3.24±0.75, and 4.47±0.60. SNR, CNR and subjective scores had significant difference among groups (all p<0.001). The optimal keV monochromatic images were superior to the 70keV monochromatic and 140kVp polychromatic images, and there was high agreement between the two observers on image quality score (kappa>0.80).
Virtual monochromatic images at approximately 63keV in dual-energy spectral CT pulmonary angiography yielded the best CNR and highest diagnostic confidence for imaging bronchial arteries.
评估在光谱CT肺血管造影中使用单色图像以提高支气管动脉图像质量的临床价值。
我们回顾性分析了38例行对比增强光谱CT的患者的胸部CT图像。这些图像包括一组140kVp的多色图像和默认的70keV单色图像。使用高级工作站(AW4.6,GE医疗)上的标准宝石光谱成像(GSI)查看器,可以自动获得用于获得动脉最佳对比噪声比(CNR)的最佳能量水平(以keV为单位)。获得这3组图像(140kVp、70keV和最佳能量水平)的信噪比(SNR)、CNR和客观图像质量评分(1-5),并进行统计学比较。还使用Kappa检验评估了两名观察者之间图像质量评分的一致性。
获得最佳CNR的最佳能量水平为62.58±2.74keV。140kVp多色图像、70keV和最佳keV单色图像的SNR和CNR分别为(16.44±5.85,13.24±5.52)、(20.79±7.45,16.69±6.27)和(24.9±9.91,20.53±8.46)。相应的主观图像质量评分为1.97±0.82、3.24±0.75和4.47±0.60。组间SNR、CNR和主观评分有显著差异(均p<0.001)。最佳keV单色图像优于70keV单色图像和140kVp多色图像,两名观察者在图像质量评分上有高度一致性(kappa>0.80)。
双能量光谱CT肺血管造影中约63keV的虚拟单色图像对支气管动脉成像产生了最佳的CNR和最高的诊断置信度。