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代谢组学技术在中医药研究中的应用。

Application of metabolomics technology in the research of Chinese medicine.

作者信息

Liu Ping, Wang Ping

机构信息

Key Laboratory of Traditional Chinese Medicine Resource and Compoumd Prescription of the Ministry of Education, Hubei University of Chinese Medicine, Wuhan, 430065, China.

出版信息

Chin J Integr Med. 2014 Apr;20(4):307-10. doi: 10.1007/s11655-014-1348-8. Epub 2014 Apr 3.

Abstract

In recent years, a novel analytical technology, metabolomics is widely used in the modern research of Chinese medicine (CM). Metabolomics adopts a "top-down" strategy to reflect the function of organisms from terminal symptoms of metabolic network and understand metabolic changes of a complete system caused by interventions. As a holistic approach, metabolomics technology, including nuclear magnetic resonance, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry, favorable to express the meaning of basic theories of CM, CM syndrome and Chinese herb. Therefore, we believe that metabolomics technology will greatly benefit to development for the research of CM in the light of modern sciences.

摘要

近年来,一种新型分析技术——代谢组学在现代中医药研究中得到广泛应用。代谢组学采用“自上而下”的策略,从代谢网络的终端症状反映生物体的功能,并了解干预引起的完整系统的代谢变化。作为一种整体方法,代谢组学技术,包括核磁共振、气相色谱 - 质谱联用和液相色谱 - 质谱联用,有利于表达中医基础理论、中医证候和中药的内涵。因此,我们认为代谢组学技术将极大地有助于中医药现代科学研究的发展。

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