Holford Theodore R, Levy David T, Meza Rafael
Department of Biostatistics, Yale School of Public Health, New Haven, CT;
Cancer Control, Department of Oncology, Georgetown University, Washington, DC;
Nicotine Tob Res. 2016 Apr;18 Suppl 1(Suppl 1):S16-29. doi: 10.1093/ntr/ntv274.
Characterizing smoking history patterns summarizes life course exposure for birth cohorts, essential for evaluating the impact of tobacco control on health. Limited attention has been given to patterns among African Americans.
Life course smoking histories of African Americans and whites were estimated beginning with the 1890 birth cohort. Estimates of smoking initiation and cessation probabilities, and intensity can be used as a baseline for studying smoking intervention strategies that target smoking exposure. US National Health Interview Surveys conducted from 1965 to 2012 yielded cross-sectional information on current smoking behavior among African Americans and whites. Additional detail for smokers including age at initiation, age at cessation and smoking intensity were available in some surveys and these were used to construct smoking histories for participants up to the date that they were interviewed. Age-period-cohort models with constrained natural splines provided estimates of current, former and never-smoker prevalence in cohorts beginning in 1890.
This approach yielded yearly estimates of initiation, cessation and smoking intensity by age for each birth cohort. Smoking initiation probabilities tend to be lower among African Americans compared to whites, and cessation probabilities also were generally lower. Higher initiation leads to higher smoking prevalence among whites in younger ages, but lower cessation leads to higher prevalence at older ages in blacks, when adverse health effects of smoking become most apparent.
These estimates provide a summary that can be used to better understand the effects of changes in smoking behavior following publication of the Surgeon General's Report in 1964.
A novel method of estimating smoking histories was applied to data from the National Health Interview Surveys, which provided an extensive summary of the smoking history in this population following publication of the Surgeon General's Report in 1964. The results suggest that some of the existing disparities in smoking-related disease may be due to the lower cessation rates in African Americans compared to whites. However, the number of cigarettes smoked is also lower among African Americans. Further work is needed to determine mechanisms by which smoking duration and intensity can account for racial disparities in smoking-related diseases.
描述吸烟史模式能够总结出生队列的一生暴露情况,这对于评估烟草控制对健康的影响至关重要。非裔美国人的吸烟模式受到的关注有限。
从1890年出生队列开始估算非裔美国人和白人的一生吸烟史。吸烟起始和戒烟概率以及吸烟强度的估算可作为研究针对吸烟暴露的吸烟干预策略的基线。1965年至2012年进行的美国国家健康访谈调查提供了非裔美国人和白人当前吸烟行为的横断面信息。在一些调查中可获得吸烟者的更多详细信息,包括起始年龄、戒烟年龄和吸烟强度,这些信息被用于构建参与者直至接受访谈时的吸烟史。带有约束自然样条的年龄-时期-队列模型提供了1890年开始的队列中当前吸烟者、曾经吸烟者和从不吸烟者患病率的估算值。
这种方法得出了每个出生队列按年龄划分的起始、戒烟和吸烟强度的年度估算值。与白人相比,非裔美国人的吸烟起始概率往往较低,戒烟概率通常也较低。较高的起始率导致白人在较年轻年龄段的吸烟患病率较高,但较低的戒烟率导致黑人在较年长年龄段的患病率较高,此时吸烟对健康的不良影响最为明显。
这些估算值提供了一个总结,可用于更好地理解1964年《美国卫生总监报告》发布后吸烟行为变化的影响。
一种估算吸烟史的新方法被应用于国家健康访谈调查的数据,该调查提供了1964年《美国卫生总监报告》发布后该人群吸烟史的广泛总结。结果表明,与吸烟相关疾病中现有的一些差异可能是由于非裔美国人的戒烟率低于白人。然而,非裔美国人的吸烟量也较低。需要进一步开展工作来确定吸烟持续时间和强度能够解释与吸烟相关疾病种族差异的机制。