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原发性和继发性干燥综合征及口干综合征的口腔黏膜表现

Oral mucosal manifestations in primary and secondary Sjögren syndrome and dry mouth syndrome.

作者信息

Błochowiak Katarzyna, Olewicz-Gawlik Anna, Polańska Adriana, Nowak-Gabryel Michalina, Kocięcki Jarosław, Witmanowski Henryk, Sokalski Jerzy

机构信息

Department of Oral Surgery, Poznan University of Medical Sciences, Poznan, Poland.

Department of Rheumatology and Clinical Immunology, Poznan University of Medical Sciences, Poznan, Poland.

出版信息

Postepy Dermatol Alergol. 2016 Feb;33(1):23-7. doi: 10.5114/pdia.2016.57764. Epub 2016 Feb 29.

DOI:10.5114/pdia.2016.57764
PMID:26985175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4793060/
Abstract

INTRODUCTION

One of the most important symptoms of Sjögren syndrome is xerostomia. The oral cavity deprived of saliva and its natural lubricative, protective and antibacterial properties is prone to a number of unfavourable consequences.

AIM

To present the most important lesions on the oral mucosa in primary and secondary Sjögren syndrome and in dry mouth syndrome.

MATERIAL AND METHODS

The study group comprised 55 patients including 52 women and 3 men aged 20-72 years (average: 28.25 years).

RESULTS

Basing on the accepted criteria, primary Sjögren syndrome was diagnosed in 22 (40%) patients, secondary Sjögren syndrome in 18 (32.7%) patients, and dry mouth syndrome in 15 (27.27%) patients. The physical examination and the examination of the mouth were performed and history was elicited from every patient.

CONCLUSIONS

The most common pathologies appearing on the oral mucosa in primary and secondary Sjögren syndrome are angular cheilitis, cheilitis, increased lip dryness as well as non-specific ulcerations, aphthae and aphthoid conditions.

摘要

引言

干燥综合征最重要的症状之一是口干。缺乏唾液及其天然润滑、保护和抗菌特性的口腔容易出现许多不良后果。

目的

介绍原发性和继发性干燥综合征以及口干综合征患者口腔黏膜的最重要病变。

材料与方法

研究组包括55例患者,其中52例女性,3例男性,年龄在20至72岁之间(平均28.25岁)。

结果

根据公认标准,22例(40%)患者诊断为原发性干燥综合征,18例(32.7%)患者诊断为继发性干燥综合征,15例(27.27%)患者诊断为口干综合征。对每位患者进行了体格检查、口腔检查并询问了病史。

结论

原发性和继发性干燥综合征患者口腔黏膜最常见的病变是口角炎、唇炎、唇部干燥加重以及非特异性溃疡、口疮和口疮样病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/4793060/1d51d7437f98/PDIA-33-26919-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/4793060/7f7aa7967588/PDIA-33-26919-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/4793060/1d51d7437f98/PDIA-33-26919-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/4793060/7f7aa7967588/PDIA-33-26919-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa77/4793060/1d51d7437f98/PDIA-33-26919-g002.jpg

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