Hyun T K, Kim H C, Kim J S
College of Agricultural, Life and Environmental Sciences, Chungbuk National University, Cheongju 361-763, Republic of Korea.
Research Institute for Hallasan, Jeju 690-816, Republic of Korea.
Indian J Pharm Sci. 2015 Nov-Dec;77(6):668-74. doi: 10.4103/0250-474x.174984.
In this study, Prunus padus, Lonicera caerulea, Berberis amurensis, and Ribes maximowiczianum, which are mainly distributed on Mt. Halla, Jeju Island, have been investigated for their antioxidant, antimicrobial, and antidiabetic activities. The methanol extracts of R. maximowiczianum leaves and P. padus branches exhibited significant and dose-dependent antioxidant activity including electron-donation ability and reducing power. To analyze the antimicrobial activity, each extract was tested by a serial two-fold dilution method against five selected gram-positive bacteria and four gram-negative bacteria, and this suggested that P. padus branches possessed the maximum antimicrobial activity against most of the gram-positive bacteria tested. In addition, the methanol extracts of P. padus branches exhibited the highest α-glucosidase inhibitory activity with an IC50 value of 1.0±0.1 μg/ml, indicating that P. padus is a promising source as a herbal medicine.
在本研究中，对主要分布于济州岛汉拿山的稠李、蓝靛果忍冬、刺黄柏和大刺茶藨子的抗氧化、抗菌和抗糖尿病活性进行了研究。大刺茶藨子叶片和稠李枝条的甲醇提取物表现出显著的、剂量依赖性的抗氧化活性，包括电子供体能力和还原能力。为分析抗菌活性，采用系列二倍稀释法对每种提取物针对5种选定的革兰氏阳性菌和4种革兰氏阴性菌进行测试，结果表明稠李枝条对大多数测试的革兰氏阳性菌具有最大抗菌活性。此外，稠李枝条的甲醇提取物表现出最高的α-葡萄糖苷酶抑制活性，IC50值为1.0±0.1μg/ml，表明稠李有望成为一种草药来源。
