Department of BIN Convergence Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756, Republic of Korea.
Department of BIN Convergence Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756, Republic of Korea; Center for Carbon Composites Materials, Department of Polymer & Nano Science and Technology, Chonbuk National University, Jeonju, Jeonbuk 561-756, Republic of Korea.
Biosens Bioelectron. 2016 Jul 15;81:445-453. doi: 10.1016/j.bios.2016.03.029. Epub 2016 Mar 15.
Herein, FeMoO4 (FM) nanorods were synthesized by a template-free, facile, hydrothermal method in an aqueous medium. The surface morphology of FeMoO4 was identified with field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). X-ray diffraction (XRD) was performed to identify the crystallographic nature of the as-synthesized FeMoO4. The as-synthesized material was used as an active electrode material for the oxidation of a neurotransmitter (i.e. norepinephrine (NE)) by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. FeMoO4 possesses polycrystallanity and bimetallic character, which helps to enhance the performance of the FM/GCE as compared to the GCE. The enhanced performance was also due to the formation of Fe (II)-dioxygen complexes, which catalyze the oxidation of NE. Meticulous observations taken from CV studies proved the diffusion-controlled nature of the reaction with a diffusion coefficient of 1.10×10(-4)cm(2)/s and a standard heterogeneous rate constant of 4.078×10(-3)cm/s. The amperometric response of NE on the FM/GCE showed a linear increase in the current between 5.0×10(-8)M and 2.0×10(-4)M with a detection limit of 3.7×10(-9)M. In the amperometric study, the time required to reach the 98% steady state response, after successive additions of 50nM NE, was less than 3s. The FM/GCE showed good sensitivity, and stability for the determination of NE.
在此，通过无模板、简便的水热法在水介质中合成了 FeMoO4（FM）纳米棒。通过场发射扫描电子显微镜（FESEM）和透射电子显微镜（TEM）对 FeMoO4 的表面形态进行了鉴定。X 射线衍射（XRD）用于鉴定合成的 FeMoO4 的晶体性质。将合成的材料用作活性电极材料，通过循环伏安法（CV）和差分脉冲伏安法（DPV）技术氧化神经递质（即去甲肾上腺素（NE））。FeMoO4 具有多晶性和双金属性质，这有助于提高 FM/GCE 的性能，与 GCE 相比。增强的性能还归因于 Fe(II)-二氧配合物的形成，其催化 NE 的氧化。从 CV 研究中仔细观察到，该反应具有扩散控制的性质，扩散系数为 1.10×10(-4)cm(2)/s，标准非均相速率常数为 4.078×10(-3)cm/s。FM/GCE 上 NE 的安培响应显示出电流在 5.0×10(-8)M 和 2.0×10(-4)M 之间的线性增加，检测限为 3.7×10(-9)M。在安培研究中，在连续添加 50nM NE 后，达到 98%稳态响应所需的时间少于 3s。FM/GCE 对 NE 的测定具有良好的灵敏度和稳定性。
