Han Jin H, Wilson Amanda, Graves Amy J, Shintani Ayumi, Schnelle John F, Ely E Wesley
Center for Quality Aging, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee.
Department of Psychiatry, Vanderbilt University Medical Center, Nashville, Tennessee.
Am J Emerg Med. 2016 Jun;34(6):1031-6. doi: 10.1016/j.ajem.2016.02.069. Epub 2016 Mar 3.
Delirium in the emergency department (ED) is an emerging field of research. Most ED research infrastructures utilize lay personnel to collect data, but delirium assessments that can be reliably performed by nonphysicians are lacking. We evaluated the diagnostic performance of the modified Brief Confusion Assessment Method (modified bCAM) for this purpose.
This was a secondary analysis of a prospective observational study that enrolled ED patients 65years or older. The original bCAM was a brief (<2minutes) delirium assessment that assessed for inattention by asking the patient to recite the months backward from December to July. It was modified by adding the Vigilance A ("squeeze my hand when you hear the letter 'A'") to the inattention assessment. The elements of the modified bCAM were performed by a research assistant (RA) and emergency physician. The reference standard for delirium was a psychiatrist assessment performed within 3hours using Diagnostic and Statistical Manual of Mental Disorder, Fourth Edition, Text Revision criteria. All assessors were blinded to each other. Sensitivities and specificities with their 95% confidence intervals (CIs) were calculated for the RA and emergency physician.
Of the 406 patients enrolled, 50 (12%) were delirious. The modified bCAM was 82.0% (95% CI, 71.4%-92.6%) sensitive and 96.1% (95% CI, 94.0%-98.1%) specific when performed by the RA. The emergency physician's modified bCAM exhibited similar diagnostic performance.
The modified bCAM may be a feasible and accurate method for nonphysicians to assess for delirium. Future studies are needed to confirm these findings.
急诊科谵妄是一个新兴的研究领域。大多数急诊科研究基础设施利用非专业人员收集数据,但缺乏可由非医生可靠执行的谵妄评估方法。为此,我们评估了改良版简易精神状态检查表(modified bCAM)的诊断性能。
这是一项对65岁及以上急诊科患者进行的前瞻性观察性研究的二次分析。原始的bCAM是一种简短(<2分钟)的谵妄评估方法,通过要求患者从12月倒着数到7月来评估注意力不集中情况。通过在注意力不集中评估中增加警觉性A(“听到字母‘A’时挤压我的手”)对其进行了改良。改良版bCAM的各项内容由一名研究助理(RA)和一名急诊科医生执行。谵妄的参考标准是由精神科医生在3小时内使用《精神疾病诊断与统计手册》第四版修订版标准进行的评估。所有评估人员相互之间均不知情。计算了RA和急诊科医生的敏感性和特异性及其95%置信区间(CI)。
在纳入的406例患者中,50例(12%)存在谵妄。RA执行改良版bCAM时,敏感性为82.0%(95%CI,71.4%-92.6%),特异性为96.1%(95%CI,94.0%-98.1%)。急诊科医生执行的改良版bCAM表现出相似的诊断性能。
改良版bCAM可能是一种非医生评估谵妄的可行且准确的方法。需要进一步的研究来证实这些发现。