Lin Shen-Fu, Chen Ying-Chen, Chen Ray-Neng, Chen Ling-Chun, Ho Hsiu-O, Tsung Yu-Han, Sheu Ming-Thau, Liu Der-Zen
Graduate Institute of Biomedical Materials and Tissue Engineering, College of Biomedical Engineering Taipei Medical University, Taipei, Taiwan (ROC).
School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan (ROC).
PLoS One. 2016 Apr 19;11(4):e0153685. doi: 10.1371/journal.pone.0153685. eCollection 2016.
There has been considerable interest in the biological functions of astaxanthin and its potential applications in the nutraceutical, cosmetics, food, and feed industries in recent years. However, the unstable structure of astaxanthin considerably limits its application. Therefore, this study reports the encapsulation of astaxanthin in calcium alginate beads using the extrusion method to improve its stability. This study also evaluates the stability of the encapsulated astaxanthin under different storage conditions. The evaluation of astaxanthin stability under various environmental factors reveals that temperature is the most influential environmental factor in astaxanthin degradation. Stability analysis shows that, regardless of the formulation used, the content of astaxanthin encapsulated in alginate beads remains above 90% of the original amount after 21 days of storage at 25°C. These results suggest that the proposed technique is a promising way to enhance the stability of other sensitive compounds.
近年来,虾青素的生物学功能及其在营养保健品、化妆品、食品和饲料行业的潜在应用受到了广泛关注。然而,虾青素不稳定的结构极大地限制了其应用。因此,本研究报道了采用挤压法将虾青素包封在海藻酸钙珠粒中以提高其稳定性。本研究还评估了包封后的虾青素在不同储存条件下的稳定性。对虾青素在各种环境因素下稳定性的评估表明,温度是影响虾青素降解的最主要环境因素。稳定性分析表明,无论使用何种配方,在25°C下储存21天后,包封在海藻酸钙珠粒中的虾青素含量仍保持在原始含量的90%以上。这些结果表明,所提出的技术是提高其他敏感化合物稳定性的一种有前景的方法。