Wu Li-Jun, Zheng Cai-Juan, Wang Liu-Kai, Han Chang-Ri, Song Xiao-Ping, Chen Guang-Ying, Zhou Xue-Ming, Wu Shou-Yuan, Li Xiao-Bao, Bai Meng, Liu Chun-Xin, Yao Jun
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Nat Prod Res. 2016 Oct;30(20):2285-90. doi: 10.1080/14786419.2016.1164699. Epub 2016 Apr 19.
One new alkaloid consanguine B (1), together with 10 known alkaloids (2-11), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua Hook.f. & Thomson collected in the Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their cytotoxic activities. Compound 1 showed weak cytotoxic activities against Hela and MCF-7 human cancer cell lines.
从采自中国海南省的斜叶暗罗（Polyalthia obliqua Hook.f. & Thomson）的枝叶乙醇提取物中，分离得到一种新生物碱近缘生物碱B（1）以及10种已知生物碱（2 - 11）。通过对综合光谱数据的详细分析阐明了它们的结构。对所有化合物进行了细胞毒性活性评估。化合物1对Hela和MCF - 7人癌细胞系显示出较弱的细胞毒性活性。
