• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在研究用全身光子计数计算机断层扫描系统上,数据补全扫描的辐射剂量能低到什么程度。

How Low Can We Go in Radiation Dose for the Data-Completion Scan on a Research Whole-Body Photon-Counting Computed Tomography System.

作者信息

Yu Zhicong, Leng Shuai, Li Zhoubo, Halaweish Ahmed F, Kappler Steffen, Ritman Erik L, McCollough Cynthia H

机构信息

From the *Department of Radiology, Mayo Clinic; and †Biomedical Engineering and Physiology Graduate Program, Mayo Graduate School, Rochester, MN; ‡Siemens Healthcare, Malvern, PA; §Siemens Healthcare, Forchheim, Germany; and ∥Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN.

出版信息

J Comput Assist Tomogr. 2016 Jul-Aug;40(4):663-70. doi: 10.1097/RCT.0000000000000412.

DOI:10.1097/RCT.0000000000000412
PMID:27096399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4949093/
Abstract

PURPOSE

A research photon-counting computed tomography (CT) system that consists of an energy-integrating detector (EID) and a photon-counting detector (PCD) was installed in our laboratory. The scanning fields of view of the EID and PCD at the isocenter are 500 and 275 mm, respectively. When objects are larger than the PCD scanning field of view, a data-completion scan (DCS) using the EID subsystem is needed to avoid truncation artifacts in PCD images. The goals of this work were to (1) find the impact of a DCS on noise of PCD images and (2) determine the lowest possible dose for a DCS such that truncation artifacts are negligible in PCD images.

METHODS

First, 2 semianthropomorphic abdomen phantoms were scanned on the PCD subsystem. For each PCD scan, we acquired 1 DCS with the maximum effective mAs and 5 with lower effective mAs values. The PCD image reconstructed using the maximum effective mAs was considered as the reference image, and those using the lower effective mAs as the test images. The PCD image reconstructed without a DCS was considered the baseline image. Each PCD image was assessed in terms of noise and CT number uniformity; the results were compared among the baseline, test, and reference images. Finally, the impact of a DCS on PCD image quality was qualitatively assessed for other body regions using an anthropomorphic torso phantom.

RESULTS

The DCS had a negligible impact on the noise magnitude in the PCD images. The PCD images with the minimum available dose (CTDIvol < 2 mGy) showed greatly enhanced CT number uniformity compared with the baseline images without noticeable truncation artifacts. Further increasing the effective mAs of a DCS did not yield noticeable improvement in CT number uniformity.

CONCLUSIONS

A DCS using the minimum available dose had negligible effect on image noise and was sufficient to maintain satisfactory CT number uniformity for the PCD scans.

摘要

目的

我们实验室安装了一种研究型光子计数计算机断层扫描(CT)系统,该系统由能量积分探测器(EID)和光子计数探测器(PCD)组成。在等中心处,EID和PCD的扫描视野分别为500和275毫米。当物体大于PCD扫描视野时,需要使用EID子系统进行数据补全扫描(DCS),以避免PCD图像中出现截断伪影。本研究的目的是:(1)找出DCS对PCD图像噪声的影响;(2)确定DCS的最低可能剂量,以使PCD图像中的截断伪影可忽略不计。

方法

首先,在PCD子系统上扫描2个半人体腹部模型。对于每次PCD扫描,我们获取1次最大有效毫安秒(mAs)的DCS和5次较低有效mAs值的DCS。使用最大有效mAs重建的PCD图像被视为参考图像,使用较低有效mAs重建的图像作为测试图像。未进行DCS重建的PCD图像被视为基线图像。对每个PCD图像的噪声和CT值均匀性进行评估;将结果在基线、测试和参考图像之间进行比较。最后,使用人体躯干模型对其他身体部位定性评估DCS对PCD图像质量的影响。

结果

DCS对PCD图像中的噪声幅度影响可忽略不计。与没有明显截断伪影的基线图像相比,具有最低可用剂量(CTDIvol < 2 mGy)的PCD图像显示出CT值均匀性大大提高。进一步增加DCS的有效mAs在CT值均匀性方面没有产生明显改善。

结论

使用最低可用剂量的DCS对图像噪声影响可忽略不计,并且足以在PCD扫描中保持令人满意的CT值均匀性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/6b9e729398f5/nihms763122f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/2d899fa7137e/nihms763122f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/d49e544d5623/nihms763122f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/f4d753cf1129/nihms763122f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/5c64c88ecc15/nihms763122f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/2d0046b52239/nihms763122f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/35db3a3983c0/nihms763122f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/e3b12d145ff4/nihms763122f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/d952c3c18acc/nihms763122f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/6b9e729398f5/nihms763122f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/2d899fa7137e/nihms763122f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/d49e544d5623/nihms763122f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/f4d753cf1129/nihms763122f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/5c64c88ecc15/nihms763122f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/2d0046b52239/nihms763122f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/35db3a3983c0/nihms763122f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/e3b12d145ff4/nihms763122f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/d952c3c18acc/nihms763122f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d55c/4949093/6b9e729398f5/nihms763122f9.jpg

相似文献

1
How Low Can We Go in Radiation Dose for the Data-Completion Scan on a Research Whole-Body Photon-Counting Computed Tomography System.在研究用全身光子计数计算机断层扫描系统上,数据补全扫描的辐射剂量能低到什么程度。
J Comput Assist Tomogr. 2016 Jul-Aug;40(4):663-70. doi: 10.1097/RCT.0000000000000412.
2
Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array.在具有光子计数探测器阵列的研究型全身CT系统中评估传统成像性能。
Phys Med Biol. 2016 Feb 21;61(4):1572-95. doi: 10.1088/0031-9155/61/4/1572. Epub 2016 Feb 2.
3
Dose Reduction for Sinus and Temporal Bone Imaging Using Photon-Counting Detector CT With an Additional Tin Filter.使用带附加锡滤过器的光子计数探测器 CT 进行鼻窦和颞骨成像的剂量降低。
Invest Radiol. 2020 Feb;55(2):91-100. doi: 10.1097/RLI.0000000000000614.
4
Multi-energy CT imaging for large patients using dual-source photon-counting detector CT.使用双源光子计数探测器 CT 对大患者进行多能量 CT 成像。
Phys Med Biol. 2020 Aug 31;65(17):17NT01. doi: 10.1088/1361-6560/ab99e4.
5
Feasibility of Dose-reduced Chest CT with Photon-counting Detectors: Initial Results in Humans.采用光子计数探测器进行低剂量胸部CT的可行性:人体初步结果
Radiology. 2017 Dec;285(3):980-989. doi: 10.1148/radiol.2017162587. Epub 2017 Jul 28.
6
Low-dose lung cancer screening with photon-counting CT: a feasibility study.低剂量光子计数CT肺癌筛查:一项可行性研究。
Phys Med Biol. 2017 Jan 7;62(1):202-213. doi: 10.1088/1361-6560/62/1/202. Epub 2016 Dec 17.
7
Human Imaging With Photon Counting-Based Computed Tomography at Clinical Dose Levels: Contrast-to-Noise Ratio and Cadaver Studies.临床剂量水平下基于光子计数的计算机断层扫描人体成像:对比噪声比及尸体研究
Invest Radiol. 2016 Jul;51(7):421-9. doi: 10.1097/RLI.0000000000000251.
8
Quantifying lumen diameter in coronary artery stents with high-resolution photon counting detector CT and convolutional neural network denoising.利用高分辨率光子计数探测器 CT 和卷积神经网络降噪技术定量冠状动脉支架内腔直径。
Med Phys. 2023 Jul;50(7):4173-4181. doi: 10.1002/mp.16415. Epub 2023 Apr 17.
9
Photon-Counting Detector CT With Denoising for Imaging of the Osseous Pelvis at Low Radiation Doses: A Phantom Study.光子计数探测器 CT 联合降噪技术在低辐射剂量下骨盆骨成像中的应用:一项体模研究。
AJR Am J Roentgenol. 2024 Jan;222(1):e2329765. doi: 10.2214/AJR.23.29765. Epub 2023 Aug 30.
10
Feasibility of multi-contrast imaging on dual-source photon counting detector (PCD) CT: An initial phantom study.基于双源光子计数探测器(PCD)CT 的多对比成像可行性:初步的体模研究。
Med Phys. 2019 Sep;46(9):4105-4115. doi: 10.1002/mp.13668. Epub 2019 Jul 5.

引用本文的文献

1
Radiation Dose Reduction in Cancer Imaging with New-Model CT Scanners: A Quality of Care Evaluation.新型CT扫描仪在癌症成像中的辐射剂量降低:护理质量评估
Cancers (Basel). 2025 May 29;17(11):1815. doi: 10.3390/cancers17111815.
2
Paediatric high-pitch lung imaging with photon-counting detector computed tomography: a dose reduction phantom study.采用光子计数探测器计算机断层扫描的儿科高音调肺部成像:一项剂量降低模型研究
Pediatr Radiol. 2025 May;55(6):1191-1201. doi: 10.1007/s00247-025-06235-0. Epub 2025 Apr 15.
3
Robustness of radiomics among photon-counting detector CT and dual-energy CT systems: a texture phantom study.

本文引用的文献

1
Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array.在具有光子计数探测器阵列的研究型全身CT系统中评估传统成像性能。
Phys Med Biol. 2016 Feb 21;61(4):1572-95. doi: 10.1088/0031-9155/61/4/1572. Epub 2016 Feb 2.
2
Human Imaging With Photon Counting-Based Computed Tomography at Clinical Dose Levels: Contrast-to-Noise Ratio and Cadaver Studies.临床剂量水平下基于光子计数的计算机断层扫描人体成像:对比噪声比及尸体研究
Invest Radiol. 2016 Jul;51(7):421-9. doi: 10.1097/RLI.0000000000000251.
3
Dual energy CT with photon counting and dual source systems: comparative evaluation.
光子计数探测器CT和双能量CT系统中放射组学的稳健性:一项纹理体模研究
Eur Radiol. 2025 Feb;35(2):871-884. doi: 10.1007/s00330-024-10976-1. Epub 2024 Jul 24.
4
Multivariate signal-to-noise ratio as a metric for characterizing spectral computed tomography.多变量信噪比作为一种用于描述能谱 CT 的指标。
Phys Med Biol. 2024 Jul 8;69(14). doi: 10.1088/1361-6560/ad5d4a.
5
Development of a separability index for task specific characterization of spectral computed tomography.用于光谱 CT 任务特异性特征描述的可分离性指数的开发。
Phys Med. 2024 Jun;122:103382. doi: 10.1016/j.ejmp.2024.103382. Epub 2024 May 30.
6
Quantification of cartilage and subchondral bone cysts on knee specimens based on a spectral photon-counting computed tomography.基于光谱光子计数 CT 的膝关节标本软骨及软骨下骨囊肿定量分析。
Sci Rep. 2023 Jul 8;13(1):11080. doi: 10.1038/s41598-023-38238-y.
7
Measurement of enhanced vasa vasorum density in a porcine carotid model using photon counting detector CT.使用光子计数探测器CT测量猪颈动脉模型中血管滋养血管密度的增强情况。
J Med Imaging (Bellingham). 2023 Jan;10(1):016001. doi: 10.1117/1.JMI.10.1.016001. Epub 2023 Feb 6.
8
High Resolution, Full Field-of-View, Whole Body Photon-Counting Detector CT: System Assessment and Initial Experience.高分辨率、全视野、全身光子计数探测器CT:系统评估与初步经验
Proc SPIE Int Soc Opt Eng. 2021 Feb;11595. doi: 10.1117/12.2581944. Epub 2021 Feb 15.
9
Quantum Iterative Reconstruction for Low-Dose Ultra-High-Resolution Photon-Counting Detector CT of the Lung.用于肺部低剂量超高分辨率光子计数探测器CT的量子迭代重建
Diagnostics (Basel). 2022 Feb 18;12(2):522. doi: 10.3390/diagnostics12020522.
10
Evaluation of Coronary Plaques and Stents with Conventional and Photon-counting CT: Benefits of High-Resolution Photon-counting CT.使用传统CT和光子计数CT评估冠状动脉斑块和支架:高分辨率光子计数CT的优势
Radiol Cardiothorac Imaging. 2021 Oct 28;3(5):e210102. doi: 10.1148/ryct.2021210102. eCollection 2021 Oct.
具有光子计数和双源系统的双能CT:对比评估
Phys Med Biol. 2015 Dec 7;60(23):8949-75. doi: 10.1088/0031-9155/60/23/8949. Epub 2015 Nov 5.
4
Performance of today's dual energy CT and future multi energy CT in virtual non-contrast imaging and in iodine quantification: A simulation study.当今双能CT及未来多能CT在虚拟平扫成像和碘定量分析中的性能:一项模拟研究。
Med Phys. 2015 Jul;42(7):4349-66. doi: 10.1118/1.4922654.
5
Initial results from a prototype whole-body photon-counting computed tomography system.一款全身光子计数计算机断层扫描系统原型的初步结果。
Proc SPIE Int Soc Opt Eng. 2015;9412. doi: 10.1117/12.2082739.
6
Vision 20/20: Single photon counting x-ray detectors in medical imaging.视野 20/20:医学成像中的单光子计数 X 射线探测器。
Med Phys. 2013 Oct;40(10):100901. doi: 10.1118/1.4820371.
7
Approximate truncation robust computed tomography--ATRACT.近似截断稳健计算断层摄影术——ATRACT。
Phys Med Biol. 2013 Sep 7;58(17):6133-48. doi: 10.1088/0031-9155/58/17/6133. Epub 2013 Aug 14.
8
Comparison of the accuracy of subtraction CT angiography performed on 320-detector row volume CT with conventional CT angiography for diagnosis of intracranial aneurysms.320 层容积 CT 减影 CT 血管成像与常规 CT 血管成像诊断颅内动脉瘤的准确性比较。
Eur J Radiol. 2012 Jan;81(1):118-22. doi: 10.1016/j.ejrad.2011.05.003. Epub 2011 May 31.
9
Volume-of-interest (VOI) imaging in C-arm flat-detector CT for high image quality at reduced dose.C 臂平板探测器 CT 中的感兴趣区(VOI)成像,可在降低剂量的情况下获得高质量图像。
Med Phys. 2010 Jun;37(6):2719-30. doi: 10.1118/1.3427641.
10
320-multidetector row whole-head dynamic subtracted CT angiography and whole-brain CT perfusion before and after carotid artery stenting: technical note.320 排多层头部动态减影 CT 血管造影及颈动脉支架置入前后全脑 CT 灌注:技术说明。
Eur J Radiol. 2010 Jun;74(3):413-9. doi: 10.1016/j.ejrad.2009.03.015. Epub 2009 May 1.