非编码调节核糖核酸在慢性炎症性疾病中的作用
[Role of non-coding regulatory ribonucleic acids in chronic inflammatory diseases].
作者信息
Heinz G A, Mashreghi M-F
机构信息
Deutsches Rheuma-Forschungszentrum (DRFZ), Charitéplatz 1, 10117, Berlin, Deutschland.
出版信息
Z Rheumatol. 2016 May;75(4):402-5. doi: 10.1007/s00393-016-0085-3.
Non-coding regulatory ribonucleic acids (RNA), including microRNA, long non-coding RNA and circular RNA, can influence the expression of genes mediating inflammatory processes and therefore affect the course and progression of chronic inflammatory diseases. Recent studies using antisense oligonucleotides suggest that such non-coding regulatory RNAs are suitable as novel therapeutic target molecules for the treatment of inflammatory rheumatic diseases.
非编码调节核糖核酸（RNA），包括微小RNA、长链非编码RNA和环状RNA，可影响介导炎症过程的基因表达，从而影响慢性炎症性疾病的病程和进展。最近使用反义寡核苷酸的研究表明，此类非编码调节RNA适合作为治疗炎性风湿性疾病的新型治疗靶点分子。
Zotero 插件