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[适应障碍与《精神疾病诊断与统计手册》第五版:综述]

[Adjustment disorder and DSM-5: A review].

作者信息

Appart A, Lange A-K, Sievert I, Bihain F, Tordeurs D

机构信息

Service de psychiatrie, clinique Saint-Luc, rue Saint-Luc 8, 5004 Bouge, Belgique.

Université Libre de Bruxelles, Bruxelles, Belgique.

出版信息

Encephale. 2017 Feb;43(1):41-46. doi: 10.1016/j.encep.2015.06.007. Epub 2016 May 20.

DOI:10.1016/j.encep.2015.06.007
PMID:27216596
Abstract

INTRODUCTION

This paper exposes the complexity and discrete characteristic of the adjustment disorder with reference to its clinical and scientific diagnosis. Even though the disorder occurs in frequent clinical circumstances after important life events, such as mobbing, burn-out, unemployment, divorce or separation, pregnancy denial, surgical operation or cancer, the adjustment disorder is often not considered in the diagnosis since better known disorders with similar symptoms prevail, such as major depression and anxiety disorder. Ten years ago, Bottéro had already noticed that the adjustment disorder diagnosis remained rather uncommon with reference to patients he was working with while Langlois assimilated this disorder with an invisible diagnosis.

METHODOLOGY

In order to maximize the data collection, we used the article review below and challenged their surveys and results: National Center for Biotechnology Information (NBCI - Pubmed) for international articles and Cairn.info for French literature. Moreover, we targeted the following keywords on the search engine and used articles, which had been published from 1 February 1975 to 31 January 2015: "adjustment", "adjustment disorder" and the French translation "trouble de l'adaptation".

RESULTS

One hundred and ninety-one articles matched our search criteria. However, after a closer analysis, solely 105 articles were selected as being of interest. Many articles were excluded since they were related to non-psychiatric fields induced by the term "adaptation". Indeed, the number of corresponding articles found for the adjustment disorder literally pointed-out the lack of existing literature on that topic in comparison to more known disorders such as anxiety disorder (2661 articles) or major depression (5481 articles). This represents up to 50 times more articles in comparison to the number of articles we found on adjustment disorder and up to 20 times more articles for the eating disorder (1994), although the prevalence is not significantly higher than for the adjustment disorder. According to their relevance and their content, we have split the articles into seven subcategories: 1. General description: most scientific articles generally describe the adjustment disorder as being a transition diagnosis, which is ambiguous, marginal and difficult to detect. The findings claim that only a few studies have been conducted on the adjustment disorder despite a high prevalence in the general population and in the clinical field. 2.

CLASSIFICATION

the DSM-5 defined the adjustment disorder as a set of different outcomes and syndromes induced by stress after a difficult life event. While the link to other disorders has not been mentioned, the diagnosis of this disorder is no longer excluded or perceived as a secondary diagnosis. The DSM-5 faced criticism from three points of view: the operationalization of the concept of stress, the differential diagnosis and the description. 3. Prevalence: different samples have shown a significantly high prevalence of the adjustment disorder within the population. In addition to the psychiatric pain induced by difficult life events we need to emphasize the fact that 12.5 to 19.4 percent of the patients faced heavy and severe pathologies and depended on clinical care and treatment. 4. Etiology, comorbidity or associated symptomatology: the literature identified the tendency to commit suicide and stressful life events as being two fundamental characteristics of adjustment disorder. The third one is the personality profile. 5.

DIFFERENTIAL DIAGNOSIS

that motivates researchers to focus on the adjustment disorder: the differentiation approach as to the major depression. Indeed, the aetiology, the symptomatology and the treatment differ from the adjustment disorder. 6.

ASSESSMENT

very recently, Dutch researchers have developed and validated the Diagnostic Interview Adjustment Disorder (DIAD). 7.

TREATMENT

in 2014, no data or meta-analysis recommended drug treatment in addition to therapy. In fact, several authors have demonstrated the ineffectiveness of drug therapy. The literature suggests a psychotherapeutic approach to treat adjustment disorder.

CONCLUSION

Emotional reactions triggered by life events are responsible for full therapy agendas and for the rush in emergency rooms and hospitals. The reflex when faced with crying, insomnia or suicidal thoughts to give a diagnostic of major depressive disorder s is generally accepted by everyone. The elevated risk to commit suicide and the approved success of remission or healing through treatment (psychotherapy) are two major reasons why several studies promote the importance and the need to identify the adjustment disorder of our patients.

摘要

引言

本文探讨了适应障碍在临床及科学诊断方面的复杂性和离散特征。尽管该障碍在诸如职场欺凌、职业倦怠、失业、离婚或分居、否认怀孕、外科手术或癌症等重大生活事件后的常见临床情况中出现,但由于存在症状相似的更为人熟知的障碍,如重度抑郁症和焦虑症,适应障碍在诊断中常常未被考虑。十年前,博泰罗就已注意到,相对于他所接触的患者而言,适应障碍的诊断仍相当罕见,而朗格卢瓦则将这种障碍视为一种难以察觉的诊断。

方法

为了最大限度地收集数据,我们查阅了以下文章并对其调查及结果提出质疑:利用美国国立生物技术信息中心(NBCI - Pubmed)获取国际文献,利用Cairn.info获取法语文献。此外,我们在搜索引擎上设定了以下关键词,并使用了1975年2月1日至2015年1月31日期间发表的文章:“适应”“适应障碍”以及法语译文“trouble de l'adaptation”。

结果

191篇文章符合我们的搜索标准。然而,经过进一步分析,仅105篇文章被选为有价值的。许多文章被排除,因为它们与由“适应”一词引发的非精神科领域相关。实际上,与诸如焦虑症(2661篇文章)或重度抑郁症(5481篇文章)等更为人熟知的障碍相比,所找到的关于适应障碍的相应文章数量着实表明该主题的现有文献匮乏。这比我们找到的关于适应障碍的文章数量多出50倍,比饮食障碍(1994篇文章)的数量多出20倍,尽管饮食障碍的患病率并不显著高于适应障碍。根据文章的相关性及其内容,我们将这些文章分为七个子类别:1. 一般描述:大多数科学文章通常将适应障碍描述为一种过渡性诊断,这种诊断模糊、边缘且难以察觉。研究结果表明,尽管在普通人群和临床领域中患病率较高,但针对适应障碍的研究却很少。2.

分类

《精神疾病诊断与统计手册》第5版(DSM - 5)将适应障碍定义为由困难生活事件后的压力引发的一组不同结果和综合征。虽然未提及与其他障碍的关联,但该障碍的诊断不再被排除或视为次要诊断。DSM - 5面临来自三个方面的批评:压力概念的操作化、鉴别诊断以及描述。3. 患病率:不同样本显示适应障碍在人群中的患病率显著较高。除了困难生活事件引发的精神痛苦外,我们还需强调这样一个事实,即12.5%至19.4%的患者面临严重和重度病症,需要临床护理和治疗。4. 病因、共病或相关症状:文献确定自杀倾向和压力性生活事件是适应障碍的两个基本特征。第三个特征是人格特征。5.

鉴别诊断

这促使研究人员关注适应障碍:与重度抑郁症的鉴别方法。实际上,重度抑郁症的病因、症状和治疗与适应障碍不同。6.

评估

最近,荷兰研究人员开发并验证了适应障碍诊断访谈(DIAD)。7.

治疗

2014年,没有数据或荟萃分析推荐除治疗外的药物治疗。事实上,几位作者已证明药物治疗无效。文献建议采用心理治疗方法来治疗适应障碍。

结论

生活事件引发的情绪反应导致了完整的治疗日程以及急诊室和医院的忙碌。面对哭泣、失眠或自杀念头时诊断为重度抑郁症的反应通常为众人所接受。自杀风险升高以及通过治疗(心理治疗)实现缓解或治愈的公认成功率是多项研究强调识别我们患者的适应障碍的重要性和必要性的两个主要原因。

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