Keswell Dheshnie, Tootla Mehreen, Goedecke Julia H
Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa.
Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa; Non-communicable Disease Research Unit, South African Medical Research Council, Cape Town, South Africa. Email:
Cardiovasc J Afr. 2016;27(3):177-183. doi: 10.5830/CVJA-2015-088. Epub 2016 May 25.
The aim was to examine differences in body fat distribution between premenopausal black and white South African (SA) women and explore the ethnic-specific associations with cardiometabolic risk.
Body composition, using dual-energy X-ray absorptiometry (DXA) and computerised tomography, insulin resistance (HOMA-IR) and lipid levels were assessed in 288 black and 197 white premenopausal SA women.
Compared to the white women, black women had less central and more peripheral (lower-body) fat, and lower serum lipid and glucose concentrations, but similar homeostasis models for insulin resistance (HOMA-IR) values. The associations between body fat distribution and HOMA-IR, triglyceride and high-density lipoprotein cholesterol concentrations were similar, while the associations with fasting glucose, total and low-density lipoprotein cholesterol levels differed between black and white women.
Ethnic differences in body fat distribution are associated, in part, with differences in cardiometabolic risk between black and white SA women.
本研究旨在探讨绝经前南非黑人和白人女性身体脂肪分布的差异，并探究特定种族与心脏代谢风险之间的关联。
采用双能X线吸收法（DXA）和计算机断层扫描评估了288名绝经前南非黑人女性和197名绝经前南非白人女性的身体成分、胰岛素抵抗（HOMA-IR）及血脂水平。
与白人女性相比，黑人女性的中心性脂肪较少，外周（下半身）脂肪较多，血清脂质和葡萄糖浓度较低，但胰岛素抵抗稳态模型评估（HOMA-IR）值相似。身体脂肪分布与HOMA-IR、甘油三酯和高密度脂蛋白胆固醇浓度之间的关联相似，而与空腹血糖、总胆固醇和低密度脂蛋白胆固醇水平的关联在黑人和白人女性中存在差异。
身体脂肪分布的种族差异部分与南非黑人和白人女性心脏代谢风险的差异有关。
