预测人工晶状体植入患者焦点透过视力的临床前指标。
Preclinical metrics to predict through-focus visual acuity for pseudophakic patients.
作者信息
Alarcon Aixa, Canovas Carmen, Rosen Robert, Weeber Henk, Tsai Linda, Hileman Kendra, Piers Patricia
机构信息
AMO Groningen, van Swietenlaan, Groningen, 9728 NX, The Netherlands.
AMO Santa Ana, CA, 1700 East St. Andrew Place Santa Ana, CA 92705, USA.
出版信息
Biomed Opt Express. 2016 Apr 15;7(5):1877-88. doi: 10.1364/BOE.7.001877. eCollection 2016 May 1.
Abstract
This study compares the clinical through-focus visual acuity (VA) in patients implanted with different intraocular lens (IOL) to optical bench testing of the same IOLs to evaluate the suitability of optical metrics of predicting clinical VA. Modulation transfer function and phase transfer function for different spatial frequencies and US Air Force pictures were measured using an optical bench for two monofocal IOLs, three multifocal IOLs and an extended range of vision IOL. Four preclinical metrics were calculated and compared to the clinical through-focus VA collected in three different clinical studies (243 patients in total). All metrics were well correlated (R(2)≥0.89) with clinical data and may be suitable for predicting through-focus VA in pseudophakic eyes.
摘要
本研究比较了植入不同人工晶状体（IOL）的患者的临床全聚焦视力（VA）与相同IOL的光学平台测试结果，以评估光学指标预测临床VA的适用性。使用光学平台测量了两种单焦点IOL、三种多焦点IOL和一种扩展视力IOL在不同空间频率下的调制传递函数和相位传递函数以及美国空军图片。计算了四个临床前指标，并与三项不同临床研究（共243例患者）中收集的临床全聚焦VA进行比较。所有指标与临床数据均具有良好的相关性（R(2)≥0.89），可能适用于预测假晶状体眼的全聚焦VA。
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