Del Águila-Carrasco Antonio J, Alarcon Aixa, Weeber Henk, Tsai Linda, Vilupuru Srividhya, Canovas Carmen, Piers Patricia
Johnson & Johnson Medtech, Groningen 9728 NX, The Netherlands.
Johnson & Johnson Medtech, Irvine, CA 92618, USA.
Biomed Opt Express. 2025 Jan 28;16(2):709-717. doi: 10.1364/BOE.540583. eCollection 2025 Feb 1.
Existing models for predicting clinical visual acuity (VA) following lens replacement surgery use controlled experimental conditions where pupil size is typically fixed. However, pupil size may influence visual performance depending on the design of the intraocular lens (IOL) implanted. This study compares optical bench testing metrics to clinical VA in pseudophakic patients with different pupil sizes and IOL models. The area under the modulation transfer function (MTFa) and the weighted optical transfer function (wOTF) were obtained at vergences ranging from -3 D to 0.5 D, and different pupil sizes: 2, 3, and 4.5 mm. The simulated VA values obtained for both metrics were well correlated with clinical data (R ≥ 0.85) and had low root mean square errors (RMSe) for the entire defocus range, suggesting their suitability for predicting VA defocus curves in pseudophakic eyes with varying pupil size.
现有的用于预测晶状体置换手术后临床视力（VA）的模型采用受控实验条件，其中瞳孔大小通常是固定的。然而，根据植入的人工晶状体（IOL）的设计，瞳孔大小可能会影响视觉性能。本研究比较了不同瞳孔大小和IOL模型的假晶状体患者的光学平台测试指标与临床VA。在从-3 D到0.5 D的不同 vergences 以及2、3和4.5 mm的不同瞳孔大小下，获得调制传递函数（MTFa）和加权光学传递函数（wOTF）的面积。两种指标获得的模拟VA值与临床数据具有良好的相关性（R≥0.85），并且在整个散焦范围内具有较低的均方根误差（RMSe），表明它们适用于预测不同瞳孔大小的假晶状体眼的VA散焦曲线。
