Olafsdottir E J, Fluge G, Haug K
Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
J Pediatr Gastroenterol Nutr. 1989 May;8(4):454-8. doi: 10.1097/00005176-198905000-00006.
The incidence of Crohn's disease (CD) and ulcerative colitis (UC) in children in western Norway was estimated in a prospective epidemiological study during the years 1984 and 1985. The total population in the area was 807,000 and the child population was 198,570 (1984). There were 27 new cases of chronic inflammatory bowel disease (IBD) in children aged 15 years or less, 10 new cases of CD, and 17 of UC. The mean annual incidence of CD in the child population was 2.5/100,000/year, whereas the incidence of UC in the child population was 4.3/100,000/year. Nearly all the children had abdominal symptoms. In this study, we found an incidence of CD in children that is the highest hitherto reported, to our knowledge. To the contrary, the incidence of UC was considerably lower than previously reported from northern Europe.
在1984年和1985年进行的一项前瞻性流行病学研究中,对挪威西部儿童克罗恩病(CD)和溃疡性结肠炎(UC)的发病率进行了估算。该地区总人口为80.7万,儿童人口为198,570人(1984年)。15岁及以下儿童中有27例新的慢性炎症性肠病(IBD)病例,其中10例为新的CD病例,17例为UC病例。儿童人群中CD的年均发病率为2.5/10万/年,而UC在儿童人群中的发病率为4.3/10万/年。几乎所有儿童都有腹部症状。据我们所知,在本研究中,我们发现儿童CD的发病率是迄今报告的最高值。相反,UC的发病率远低于北欧此前报告的发病率。