Mulligan Hilda, Wilkinson Amanda, Barclay Amelia, Whiting Hayley, Heynike Christelle, Snowdon Jessie
Centre for Health, Activity, and Rehabilitation Research, School of Physiotherapy, University of Otago, Dunedin, New Zealand (HM, AW); School of Physiotherapy, University of Otago, Dunedin, New Zealand (AB, HW, CH); and Multiple Sclerosis and Parkinson's Society Canterbury Inc, Christchurch, New Zealand (JS).
Int J MS Care. 2016 May-Jun;18(3):116-21. doi: 10.7224/1537-2073.2015-019.
Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The program "Minimise Fatigue, Maximise Life: Creating Balance with Multiple Sclerosis" (MFML) was created in New Zealand because of the lack of a fatigue management program for people with MS in that country. This program aims to empower individuals with MS to manage their own symptoms of fatigue. The objective of this study was to evaluate the MFML fatigue self-management program.
Self-report questionnaires were used to measure impact of fatigue (5-item Modified Fatigue Impact Scale), self-efficacy (MS Self-efficacy Scale), and quality of life (12-item Short Form Health Status Survey [SF-12]) 1 month before (T1), at commencement of (T2) (to investigate the stability of questionnaire scores before the intervention), and at the end of (T3) the 6-week group-based program. Increased self-efficacy and quality of life scores and a decrease in reported impact of fatigue were the anticipated primary outcomes, with participants acting as their own controls.
Twenty-five women (aged 37-63 years) participated. Stability of scores for all the questionnaires was evidenced between T1 and T2. After the intervention (T3), scores showed a significant improvement in self-efficacy and impact of fatigue, with large effect sizes, but no change in either the physical or mental component summary of the SF-12.
Despite the small sample size, this study showed an organized approach to the management of fatigue for people living with MS, and its outcomes demonstrated benefits for participants.
疲劳是多发性硬化症（MS）最常见且使人衰弱的症状之一。由于新西兰缺乏针对MS患者的疲劳管理项目，故而创建了“将疲劳降至最低，最大化生活：与多发性硬化症保持平衡”（MFML）项目。该项目旨在使MS患者有能力管理自身的疲劳症状。本研究的目的是评估MFML疲劳自我管理项目。
采用自我报告问卷在干预前1个月（T1）、干预开始时（T2）（以调查干预前问卷分数的稳定性）以及为期6周的基于小组的项目结束时（T3）测量疲劳影响（5项改良疲劳影响量表）、自我效能感（MS自我效能感量表）和生活质量（12项简短健康状况调查问卷[SF - 12]）。预期的主要结果是自我效能感和生活质量得分增加以及报告的疲劳影响降低，参与者作为自身对照。
25名女性（年龄37 - 63岁）参与了研究。T1和T2之间所有问卷的分数都显示出稳定性。干预后（T3），自我效能感和疲劳影响得分有显著改善，效应量较大，但SF - 12的身体或心理成分总结均无变化。
尽管样本量较小，但本研究表明针对MS患者的疲劳管理有了一种有组织的方法，其结果显示对参与者有益。
