Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.
Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.
Environ Int. 2016 Sep;94:170-176. doi: 10.1016/j.envint.2016.05.016. Epub 2016 May 31.
Exposure to road traffic noise has been associated with adiposity and diabetes in adults. The suggested pathways have been through sleep disturbance and stress. Children may be particularly susceptible to noise induced sleep disturbance and stress and the effects hereof.
To examine the association between traffic noise exposure during pregnancy and early childhood and adiposity in children.
We identified 40,974 singletons from the Danish National Birth Cohort with parentally given questionnaire information on weight and height at 7-years of age. Road and railway traffic noise were modeled at all historical addresses and expressed as time-weighted means for two exposure periods (pregnancy and childhood). Adiposity was assessed using BMI z-scores and a dichotomous measure of childhood overweight based on age and sex specific cut-offs. Associations were analyzed using linear regression for BMI z-scores and logistic regression for risk of childhood overweight, adjusting for socioeconomic position, maternal BMI, maternal smoking, maternal age, parity and degree of urbanization.
We found both pregnancy and childhood exposure to road traffic noise to be associated with a higher risk for childhood overweight (odds ratio (OR)=1.06 per 10dB, 95% confidence interval (CI): 1.00-1.12 for exposure during pregnancy and OR=1.06 per 10dB, 95% CI: 0.99-1.12 for childhood exposure). There were no associations between road traffic noise and BMI z-scores. We found no associations between railway noise and adiposity.
We found suggestions of a positive association between road traffic noise and risk of overweight in 7-years old children.
暴露于道路交通噪声与成年人肥胖和糖尿病有关。其可能的途径是通过睡眠障碍和压力。儿童可能特别容易受到噪声引起的睡眠障碍和压力的影响。
研究孕妇和幼儿期道路交通噪声暴露与儿童肥胖的关系。
我们从丹麦国家出生队列中确定了 40974 名单胎儿童，这些儿童的父母在 7 岁时提供了体重和身高的问卷调查信息。道路和铁路交通噪声在所有历史地址进行建模，并表示为两个暴露期（孕期和儿童期）的时间加权平均值。肥胖程度采用 BMI z 分数和基于年龄和性别特定切点的儿童超重的二分测量来评估。使用线性回归分析 BMI z 分数，使用逻辑回归分析儿童超重的风险，调整社会经济地位、母亲 BMI、母亲吸烟、母亲年龄、产次和城市化程度。
我们发现，孕期和儿童期接触道路交通噪声都与儿童超重的风险增加有关（暴露于孕期时，每增加 10dB，比值比（OR）为 1.06，95%置信区间（CI）为 1.00-1.12；儿童期暴露时，OR 为 1.06，95%CI 为 0.99-1.12）。道路交通噪声与 BMI z 分数之间没有关联。我们没有发现铁路噪声与肥胖的关系。
我们发现道路交通噪声与 7 岁儿童超重风险之间存在正相关的迹象。
