Okubo T, Ishihara N, Oura A, Serit M, Kim M, Yamamoto T, Mitsuoka T
a Central Research Laboratories, Taiyo Kagaku Co., Ltd. , Yokkaichi Mie 510 , Japan.
b Department of Biotechnology , Fukuyama University , Fukuyama , Hiroshima 729-02 , Japan.
Biosci Biotechnol Biochem. 1992 Jan;56(4):588-91. doi: 10.1271/bbb.56.588.
Effects of tea polyphenol intake (0.4 g/volunteer, 3 times per day, for four weeks) on fecal microflora, bacterial metabolites, and pH were investigated using eight healthy human volunteers. Counts for Clostridium perfringens and other Clostridium spp. were significantly decreased during the tea polyphenol intake periods. Percentage of volunteers having C. perfringens in their feces decreased significantly, but not for other Clostridium spp. Percentage of Bifidobacterium spp. (the acid forming bacteria) in total counts and the content of volatile fatty acids including acetic and propionic acids increased significantly, which might have reduced the fecal pH. However, the tea polyphenols had no effect on fecal enzyme activities, ammonia, or putrefactive products. Two weeks after discontinuing the intake, the microflora counts and their biological parameters appeared to have returned to normal.
使用8名健康志愿者研究了茶多酚摄入量（0.4克/志愿者，每天3次，持续四周）对粪便微生物群、细菌代谢产物和pH值的影响。在摄入茶多酚期间，产气荚膜梭菌和其他梭菌属的数量显著减少。粪便中产气荚膜梭菌的志愿者百分比显著下降，但其他梭菌属没有。双歧杆菌属（产酸菌）在总数中的百分比以及包括乙酸和丙酸在内的挥发性脂肪酸含量显著增加，这可能降低了粪便pH值。然而，茶多酚对粪便酶活性、氨或腐败产物没有影响。停止摄入两周后，微生物群数量及其生物学参数似乎已恢复正常。
