Lam Kit Ying, Ling Anna Pick Kiong, Koh Rhun Yian, Wong Ying Pei, Say Yee How
School of Postgraduate Studies and Research, International Medical University, 57000 Kuala Lumpur, Malaysia.
Division of Biomedical Science and Biotechnology, School of Health Sciences, International Medical University, 57000 Kuala Lumpur, Malaysia.
Adv Pharmacol Sci. 2016;2016:4104595. doi: 10.1155/2016/4104595. Epub 2016 May 19.
Medicinal plants continue to play an important role in modern medications and healthcare as consumers generally believe that most of them cause fewer or milder adverse effects than the conventional modern medicines. In order to use the plants as a source of medicinal agents, the bioactive compounds are usually extracted from plants. Therefore, the extraction of bioactive compounds from medicinal plants is a crucial step in producing plant-derived drugs. One of the bioactive compounds isolable from medicinal plants, orientin, is often used in various bioactivity studies due to its extensive beneficial properties. The extraction of orientin in different medicinal plants and its medicinal properties, which include antioxidant, antiaging, antiviral, antibacterial, anti-inflammation, vasodilatation and cardioprotective, radiation protective, neuroprotective, antidepressant-like, antiadipogenesis, and antinociceptive effects, are discussed in detail in this review.
药用植物在现代药物和医疗保健中继续发挥着重要作用，因为消费者普遍认为，与传统现代药物相比，大多数药用植物产生的不良反应更少或更轻微。为了将植物用作药物来源，通常从植物中提取生物活性化合物。因此，从药用植物中提取生物活性化合物是生产植物源药物的关键步骤。从药用植物中可分离出的生物活性化合物之一——荭草素，由于其广泛的有益特性，常被用于各种生物活性研究。本文详细讨论了荭草素在不同药用植物中的提取及其药用特性，这些特性包括抗氧化、抗衰老、抗病毒、抗菌、抗炎、血管舒张和心脏保护、辐射防护、神经保护、抗抑郁样、抗脂肪生成和抗伤害感受作用。
