Gong Hongxia, Song Qiuying, Wang Lanhui
Department of Traditional Chinese Medicine, Tianjin Eye Hospital, Tianjin Medical University, Heping, Tianjin 300000, P.R. China.
Visual Function Inspection Section, Tianjin Eye Hospital, Tianjin Medical University, Heping, Tianjin 300000, P.R. China.
Exp Ther Med. 2016 Jun;11(6):2420-2424. doi: 10.3892/etm.2016.3175. Epub 2016 Mar 21.
The aim of this study was to investigate the association between central visual impairment and the characteristics of fundus fluorescein angiography (FFA) in patients with central retinal artery occlusion (CRAO). A total of 63 patients were diagnosed with CRAO by FFA. The visual dysfunction was classified into severe, mild and light degrees. Tropicamide was administered for mydriasis. FFA examination was performed using Heidelberg retinal tomography. The associations of age, gender and disease course with CRAO type were analyzed. Three types of manifestations were identified by FFA in 63 eyes, including poor perfusion (18 cases), exudation (22 cases) and mixed types (23 cases) of CRAO. No significant difference was found in age (F=0.171, P=0.844) and disease course (F=0.016, P=0.984) among the three types of CRAO. Similarly, no significant difference was found in gender among the three types of CRAO (χ=0.176, P=0.916). The damage to vision caused by the exudation type of CRAO was not as severe as that caused by the poor perfusion and mixed types of CRAO. The distributions of damage severity caused by the poor perfusion and mixed types of CRAO were similar. In conclusion, the FFA observations for CRAO can be classified into three types of manifestations. The damage to vision in patients with CRAO is likely to be associated with poor perfusion in the retinal artery rather than exudation affecting the retina or optic disc. The patterns of clinical manifestations are not associated with age, gender or disease course.
本研究旨在探讨视网膜中央动脉阻塞（CRAO）患者的中心视力损害与眼底荧光血管造影（FFA）特征之间的关联。共有63例患者通过FFA诊断为CRAO。视觉功能障碍分为重度、轻度和轻度。使用托吡卡胺进行散瞳。采用海德堡视网膜断层扫描进行FFA检查。分析年龄、性别和病程与CRAO类型的关联。通过FFA在63只眼中识别出三种表现类型，包括灌注不良型（18例）、渗出型（22例）和混合型（23例）CRAO。三种类型的CRAO在年龄（F = 0.171，P = 0.844）和病程（F = 0.016，P = 0.984）方面未发现显著差异。同样，三种类型的CRAO在性别方面也未发现显著差异（χ = 0.176，P = 0.916）。渗出型CRAO对视力造成的损害不如灌注不良型和混合型CRAO严重。灌注不良型和混合型CRAO造成的损害严重程度分布相似。总之，CRAO的FFA观察结果可分为三种表现类型。CRAO患者的视力损害可能与视网膜动脉灌注不良有关，而非渗出影响视网膜或视盘。临床表现模式与年龄、性别或病程无关。
