Zhao Chun, Zhang Fangbiao, Zhang Xiangyan, Tu Shaosong, Wu Zhijun, Li Xia, Xiang Yingming, Zheng Chunhui, Zeng Qinghui
Department of Cardiothoracic Surgery, Lishui Center Hospital, Lishui, Zhejiang 323000, P.R. China.
Oncol Lett. 2016 Jun;11(6):3782-3784. doi: 10.3892/ol.2016.4453. Epub 2016 Apr 18.
Primary mediastinal liposarcomas are extremely rare. The current study reports the case of a 63-year-old man presenting with a primary liposarcoma arising from the posterior mediastinum. The patient reported a 6-month history of chest pain with increasing dyspnea for 2 months. Enhanced computed tomography revealed a 10×16-cm mass in the posterior mediastinum. Other physical examinations were normal. Radical resection was performed under the agreement of patient. Subsequent pathological analysis indicated a liposarcoma. The patient recovered and was successfully discharged. However, at a follow-up examination 12 months after surgery, recurrence was identified in the anterior mediastinum. Therefore, the patient underwent surgery. The postoperative course was uneventful, however, there was evidence of disease recurrence 2 years after the second surgery. The patient refused any treatment and succumbed after 3 months.
原发性纵隔脂肪肉瘤极为罕见。本研究报告了一例63岁男性患者，其原发性脂肪肉瘤起源于后纵隔。患者自述胸痛6个月，伴进行性呼吸困难2个月。增强计算机断层扫描显示后纵隔有一个10×16厘米的肿块。其他体格检查均正常。在患者同意下进行了根治性切除术。随后的病理分析表明为脂肪肉瘤。患者康复并顺利出院。然而，在术后12个月的随访检查中，发现前纵隔复发。因此，患者接受了手术。术后过程顺利，然而，第二次手术后2年有疾病复发的证据。患者拒绝任何治疗，3个月后死亡。
