Møss J
Dumex Ltd, Copenhagen, Denmark.
Skin Res Technol. 1996 Feb;2(1):32-6. doi: 10.1111/j.1600-0846.1996.tb00052.x.
BACKGROUND/AIMS: The hydrating properties of three moisturising preparations, commonly recommended for the treatment of dry skin, were compared by utilising non-invasive measuring methods.
The preparations were Decubal®/Abitima® cream, Dumex Ltd; pH5-Eucerin® ointment, Beiersdorf; and Essex® cream, Schering Plough. Skicon-200® and a Corneometer CM 420® were used for assessment of skin hydration. Readings of the transepidermal water loss (TEWL) and skin temperature were also taken. The study was conducted in 2 parts, each with 12 women. The preparations were applied to a designated area on the forearms 2× a day for 7 days; the 4th, untreated, area served as control. Readings were taken before the start of treatment and every morning during the treatment period and the following week.
Both electrical measuring methods showed that hydration of the stratum corneum increased after a few days of treatment, especially after the application of Decubal®/Abitima®. TEWL was not affected by any of the treatments.
The two electrical methods ranked the products consistently, i.e. Decubal®/Abitima® >pH5-Eucerin® >Essex®. Conductance (Skicon-200) was more discriminative than capacitance (Corneometer CM420). However, these methods are not water specific. TEWL was not affected by the treatments.
背景/目的:通过使用非侵入性测量方法,比较了三种常用于治疗干性皮肤的保湿制剂的保湿性能。
这些制剂分别是德库巴尔®/阿比蒂玛®乳膏(杜美丝有限公司)、pH5-优色林®软膏(拜尔斯道夫公司)和埃塞克斯®乳膏(先灵葆雅公司)。使用Skicon-200®和角质层水合测量仪CM 420®评估皮肤水合作用。还测量了经表皮水分流失(TEWL)和皮肤温度。该研究分两部分进行,每部分有12名女性。将制剂每天两次涂抹于前臂的指定区域,持续7天;第4个未处理区域作为对照。在治疗开始前以及治疗期间和接下来一周的每天早晨进行测量。
两种电学测量方法均显示,治疗几天后角质层的水合作用增强,尤其是在涂抹德库巴尔®/阿比蒂玛®之后。TEWL不受任何一种治疗的影响。
两种电学方法对产品的排名一致,即德库巴尔®/阿比蒂玛®>pH5-优色林®>埃塞克斯®。电导率(Skicon-200)比电容(角质层水合测量仪CM420)更具区分性。然而,这些方法并非针对水的特异性方法。TEWL不受治疗影响。