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Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.慢性氯胺酮滥用相关的胆汁淤积和胆管扩张:病例系列研究。
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BJU Int. 2011 Jun;107(12):1881-4. doi: 10.1111/j.1464-410X.2010.10031.x. Epub 2011 Feb 14.
3
Emergency department presentation of ketamine abusers in Hong Kong: a review of 233 cases.香港氯胺酮滥用者在急诊科的表现:233 例病例回顾。
Hong Kong Med J. 2010 Feb;16(1):6-11.
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Dilated common bile ducts mimicking choledochal cysts in ketamine abusers.氯胺酮滥用者中酷似胆总管囊肿的扩张胆总管。
Hong Kong Med J. 2009 Feb;15(1):53-6.
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J Anal Toxicol. 2005 Jul-Aug;29(5):376-82. doi: 10.1093/jat/29.5.376.
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A review of the nonmedical use of ketamine: use, users and consequences.氯胺酮非医疗用途综述:使用情况、使用者及后果
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7
Location of enkephalinase and functional effects of [Leu5]enkephalin and inhibition of enkephalinase in the feline main pancreatic and bile duct sphincters.脑啡肽酶在猫主胰管和胆管括约肌中的定位以及[亮氨酸5]脑啡肽的功能作用和脑啡肽酶的抑制作用
Clin Sci (Lond). 1992 Feb;82(2):169-73. doi: 10.1042/cs0820169.

与氯胺酮滥用相关的慢性胆绞痛。

Chronic biliary colic associated with ketamine abuse.

作者信息

Al-Nowfal Ahmed, Al-Abed Yahya A

机构信息

Department of Surgery, Southend University Hospital, Prittlewell Chase, Westcliff-on-Sea, Essex, UK.

出版信息

Int Med Case Rep J. 2016 Jun 2;9:135-7. doi: 10.2147/IMCRJ.S100648. eCollection 2016.

DOI:10.2147/IMCRJ.S100648
PMID:27330331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4898409/
Abstract

INTRODUCTION

Biliary colic is a common clinical presentation, with the majority of cases being related to gallstone disease. However, rarely, patients may present with biliary symptoms without evidence of gallbladder stones - referred to as acalculous gallstone disease. This case report details a rare case of chronic biliary colic associated with ketamine abuse.

CASE PRESENTATION

A 24-year-old Caucasian female presented to the emergency department with a history of intermittent right upper quadrant pain associated with nausea and malaise. She had experienced bouts of similar symptoms three times a year for the past 4 years. Various investigations had been conducted during her multiple admissions, which showed possible dilatation of the common bile duct, with no evidence of gallstones.

CONCLUSION

Patients can present with a dilated common bile duct and an acalculous cholecystitis. This requires considerable investigation, with an emphasis on drug history, especially with the current rise of recreational hallucinogenic drug abuse.

摘要

引言

胆绞痛是一种常见的临床表现,大多数病例与胆结石疾病有关。然而,罕见的是,患者可能出现胆道症状但无胆囊结石证据——称为无结石性胆结石疾病。本病例报告详细介绍了一例与氯胺酮滥用相关的罕见慢性胆绞痛病例。

病例介绍

一名24岁的白人女性因间歇性右上腹疼痛伴恶心和不适的病史就诊于急诊科。在过去4年中,她每年经历三次类似症状发作。在她多次入院期间进行了各种检查,结果显示胆总管可能扩张,无胆结石证据。

结论

患者可能出现胆总管扩张和无结石性胆囊炎。这需要进行大量检查,尤其要重视用药史,特别是鉴于目前娱乐性致幻药物滥用情况的增加。