Lucassen G W, van der Sluys W L, van Herk J J, Nuijs A M, Wierenga P E, Barel A O, Lambrecht R
Personal Care Institute, Philips Research, Eindhoven, The NetherlandsLaboratory of General and Biological Chemistry, Faculty of Physical Education and Physiotherapy, Tree University of Brussels, Brussels, Belgium.
Skin Res Technol. 1997 Aug;3(3):154-60. doi: 10.1111/j.1600-0846.1997.tb00180.x.
BACKGROUND/AIMS: The visual appearance of cellulite or the'orange peel'look of skin is a common cosmetic problem for many women. Cellulite, or more correctly lipodystrophy, is a modification of the adipose tissue, whereby the fat lobules are swollen as the result of a disturbed blood and lymph micro-circulation and fibrosclerose of connective tissue. In the wealthy diversity of products against cellulite, objective methods to measure their efficacy are of growing importance. The purpose of this study is to establish the effectiveness of a skin massage treatment by quantifying the changes in the skin via ultrasound imaging, during and following treatment.
Using 20 MHz C-mode ultrasound scanning, a three-dimensional subsurface is constructed that represents the dermis-hypodermis tissue interface. In normal cellulite-free skin, this interface is smooth. In the case of cellulite, however, the dermis-hypodermis junction appears as an irregular surface. Qualitatively, the effect of cellulite treatment is inferred from changes in the shape of this junction. In order to quantify the effect, we chose to monitor the junction area. For the treatments, we used a specially designed handheld electro-mechanical massage device that was moved along the thigh. Treatments were conducted for 3 months, three times a week, during 15 min on each upper leg of 20 healthy female volunteers with moderate symptoms of cellulite (Curri's classification 1-2). Ultrasound measurements were performed monthly, and continued for 2 months after the treatments were stopped.
The results, on average, indicate a significant smoothening of the dermis-hypodermis surface (relative surface area reduction 34+3%, 50±3% and 56±2% after 1, 2 and 3 months of treatment, respectively). The smoothening can be described by a mono-exponential function with a time constant of 1.1 month. After the treatments were discontinued, the relative surface area gradually increased (with a time constant of 2.6 month), which indicates that the effect of massage is not permanent.
Treatment of cellulite by means of an electro-mechanical skin fold massage apparatus significantly smoothens the structure of the dermis-hypodermis interface. Three-dimensional ultrasound imaging of the dermis-hypodermis junction could serve as an objective method to monitor the effectiveness of cellulite treatment.
背景/目的:橘皮组织的外观,即皮肤呈现出的“橘皮样”外观,是许多女性常见的美容问题。橘皮组织,或者更准确地说是脂肪营养不良,是脂肪组织的一种改变,由于血液和淋巴微循环紊乱以及结缔组织纤维硬化,脂肪小叶会肿胀。在琳琅满目的抗橘皮组织产品中,衡量其功效的客观方法变得越来越重要。本研究的目的是通过超声成像量化治疗期间及治疗后皮肤的变化,从而确定皮肤按摩治疗的效果。
使用20兆赫的C模式超声扫描构建一个代表真皮 - 皮下组织界面的三维皮下结构。在没有橘皮组织的正常皮肤中,这个界面是光滑的。然而,在有橘皮组织的情况下,真皮 - 皮下连接表现为不规则表面。定性地说,橘皮组织治疗的效果可从该连接形状的变化推断出来。为了量化效果,我们选择监测连接面积。对于治疗,我们使用了一种专门设计的手持式机电按摩装置,该装置沿着大腿移动。对20名有中度橘皮组织症状(库里分类1 - 2级)的健康女性志愿者的每条大腿进行治疗,为期3个月,每周3次,每次15分钟。每月进行超声测量,并在治疗停止后持续2个月。
平均结果表明真皮 - 皮下表面有显著的平滑化(治疗1、2和3个月后相对表面积分别减少34±3%、50±3%和56±2%)。平滑化可用时间常数为1.1个月的单指数函数来描述。治疗停止后,相对表面积逐渐增加(时间常数为2.6个月),这表明按摩效果不是永久性的。
通过机电皮肤褶皱按摩仪治疗橘皮组织可显著使真皮 - 皮下界面结构平滑。真皮 - 皮下连接的三维超声成像可作为监测橘皮组织治疗效果的客观方法。