Gauffin Emelie, Öster Caisa, Sjöberg Folke, Gerdin Bengt, Ekselius Lisa
Department of Neuroscience Psychiatry, Uppsala University, University Hospital, SE-751 85 Uppsala,Sweden; The Burn Center, Department of Hand, Plastic and Intensive, Linköping University, 581 85 Linköping, Sweden.
Department of Neuroscience Psychiatry, Uppsala University, University Hospital, SE-751 85 Uppsala,Sweden.
Burns. 2016 Dec;42(8):1781-1788. doi: 10.1016/j.burns.2016.05.016. Epub 2016 Jun 21.
Chronic pain after burn can have severe physical and psychological effects on former patients years after the initial injury. Although the issue of pain after burn has gained increased attention over the past years, prospective, longitudinal studies are scarce. Our aim was to prospectively investigate consecutive burn patients for pain severity over time and to evaluate the prevalence and characteristics of post-burn pain to 2-7 years after the burn. As an additional aim, the effects of burn and individual-related factors, especially health-related Quality of Life (HRQoL), were investigated.
Sixty-seven consecutive burn patients were assessed during acute care at 3, 6, 12 and 24 months, as well as at 2-7 years post-burn. HRQoL, symptoms of post-traumatic stress disorder (PTSD) and other psychiatric disorders were investigated. During the interviews that took place 2-7 years after the injury (mean 4.6±1.9 years), current chronic post-burn pain was assessed using the Brief Pain Inventory-Short Form (BPI-SF).
One-third of the patients still reported pain 2-7 years after the injury. Pain severity and interference with daily life were mainly mild to moderate though they were found to be associated with significantly lower HRQoL. Chronic pain after burn was associated with both burn- and individual-related factors. In logistic regression analysis HRQoL at 3 and 12 months and symptoms of PTSD at 12 months were independent factors in predicting chronic pain after burn.
Pain after burn becomes a chronic burden for many former burn patients and decreases HRQoL. A novel finding in this study was that HRQoL assessed early after burn was a predictor for the development of chronic pain. This finding may help to predict future pain problems and serve as an indicator for pain preventive measures.
烧伤后的慢性疼痛在初次受伤数年之后会对患者产生严重的生理和心理影响。尽管在过去几年中,烧伤后疼痛问题已受到越来越多的关注,但前瞻性的纵向研究仍然匮乏。我们的目的是对连续性烧伤患者的疼痛严重程度进行前瞻性长期调查,并评估烧伤后2至7年的烧伤后疼痛的患病率及特征。另外一个目的是调查烧伤及个体相关因素的影响,尤其是健康相关生活质量(HRQoL)。
对67例连续性烧伤患者在急性护理期间的3、6、12和24个月以及烧伤后2至7年进行评估。调查了HRQoL、创伤后应激障碍(PTSD)症状及其他精神障碍。在受伤后2至7年(平均4.6±1.9年)进行的访谈中,使用简明疼痛量表简表(BPI-SF)评估当前的慢性烧伤后疼痛。
三分之一的患者在受伤后2至7年仍报告有疼痛。疼痛严重程度及对日常生活的干扰主要为轻度至中度,不过发现其与显著更低的HRQoL相关。烧伤后慢性疼痛与烧伤及个体相关因素均有关。在逻辑回归分析中,3个月和12个月时的HRQoL以及12个月时的PTSD症状是预测烧伤后慢性疼痛的独立因素。
烧伤后疼痛成为许多烧伤患者的慢性负担,并降低了HRQoL。本研究中的一个新发现是,烧伤后早期评估的HRQoL是慢性疼痛发生的一个预测指标。这一发现可能有助于预测未来的疼痛问题,并作为疼痛预防措施的一个指标。