Franik Grzegorz, Krysta Krzysztof, Madej Paweł, Gimlewicz-Pięta Beata, Oślizło Barbara, Trukawka Justina, Olszanecka-Glinianowicz Magdalena
a Department of Endocrinological Gynaecology , Medical University of Silesia , Katowice , Poland.
b Department of Rehabilitation Psychiatry , Medical University of Silesia , Katowice , Poland.
Gynecol Endocrinol. 2016 Dec;32(12):1014-1017. doi: 10.1080/09513590.2016.1196177. Epub 2016 Jun 27.
Sleep disturbances in women with Polycystic Ovary Syndrome (PCOS) have been reported in recent years. The majority of published studies are related to Obstructive Sleep Apnea (OSA) while not many researches have analyzed any other causes of sleep disturbances. A group of ninety five women with Polycystic Ovary Syndrome were enrolled into the study. Sleep disturbances were assessed using validated questionnaires. On the grounds of Athens Insomnia Scale (AIS) evaluation a clinically significant insomnia was ascertained in 12.6% of women with PCOS, while according to Insomnia Severity Index (ISI) in 10.5%. Clinically significant insomnia according to both AIS and ISI, occurred significantly more often in women with PCOS than in women without PCOS based on the chi-square test. The Mann-Whitney U test revealed statistically significant difference between women with and without PCOS based on total values of ISI. An excessive daytime sleepiness occurred at 7.4% of women with PCOS. Statistically significant dependance between: clinically significant insomnia in both AIS and ISI and excessive daytime sleepiness indicated by Epworth Sleepiness Scale (ESS) was observed. Sleep disorders are common in women with PCOS. Screening assessment of sleep disturbances should be a part of medical diagnostics in women with PCOS.
近年来,多囊卵巢综合征(PCOS)女性的睡眠障碍问题已被报道。大多数已发表的研究都与阻塞性睡眠呼吸暂停(OSA)有关,而对睡眠障碍的其他原因进行分析的研究并不多。一组95名多囊卵巢综合征女性被纳入该研究。使用经过验证的问卷对睡眠障碍进行评估。根据雅典失眠量表(AIS)评估,12.6%的PCOS女性被确定存在具有临床意义的失眠,而根据失眠严重程度指数(ISI),这一比例为10.5%。根据卡方检验,基于AIS和ISI两者都存在具有临床意义的失眠在PCOS女性中比在无PCOS女性中更频繁地出现。曼-惠特尼U检验显示,基于ISI的总值,有PCOS和无PCOS的女性之间存在统计学上的显著差异。7.4%的PCOS女性出现白天过度嗜睡。观察到在AIS和ISI中具有临床意义的失眠与由爱泼华嗜睡量表(ESS)表明的白天过度嗜睡之间存在统计学上的显著相关性。睡眠障碍在PCOS女性中很常见。对睡眠障碍的筛查评估应成为PCOS女性医学诊断的一部分。