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Cohort Profile Update: The British Regional Heart Study 1978-2014: 35 years follow-up of cardiovascular disease and ageing.队列研究概况更新:英国地区心脏研究(1978 - 2014年):心血管疾病与衰老的35年随访
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Sleep as a potential fundamental contributor to disparities in cardiovascular health.睡眠作为心血管健康差异的一个潜在根本因素。
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Sleep. 2014 May 1;37(5):851-8. doi: 10.5665/sleep.3646.
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Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population.日间小睡与全因和特定原因死亡率的风险:一项对英国人群进行的 13 年随访研究。
Am J Epidemiol. 2014 May 1;179(9):1115-24. doi: 10.1093/aje/kwu036. Epub 2014 Mar 30.
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Snoring, daytime sleepiness, and incident cardiovascular disease in the health, aging, and body composition study.打鼾、日间嗜睡与健康、衰老和身体成分研究中的心血管疾病事件。
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Inequalities in heart failure in older men: prospective associations between socioeconomic measures and heart failure incidence in a 10-year follow-up study.老年男性心力衰竭中的不平等现象:10 年随访研究中社会经济措施与心力衰竭发生率之间的前瞻性关联。
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自我报告的睡眠时间、午睡与心力衰竭事件:英国地区心脏研究中的前瞻性关联

Self-Reported Sleep Duration, Napping, and Incident Heart Failure: Prospective Associations in the British Regional Heart Study.

作者信息

Wannamethee S Goya, Papacosta Olia, Lennon Lucy, Whincup Peter H

机构信息

Department of Primary Care and Population Health, University College, London, United Kingdom.

Population Health Research Institute, St George's, University of London, London, United Kingdom.

出版信息

J Am Geriatr Soc. 2016 Sep;64(9):1845-50. doi: 10.1111/jgs.14255. Epub 2016 Jun 28.

DOI:10.1111/jgs.14255
PMID:27351127
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5031211/
Abstract

OBJECTIVES

To examine the associations between self-reported nighttime sleep duration and daytime sleep and incident heart failure (HF) in men with and without preexisting cardiovascular disease (CVD).

DESIGN

Population-based prospective study.

SETTING

General practices in 24 British towns.

PARTICIPANTS

Men aged 60-79 without prevalent HF followed for 9 years (N = 3,723).

MEASUREMENTS

Information on incident HF cases was obtained from primary care records. Assessment of sleep was based on self-reported sleep duration at night and daytime napping.

RESULTS

Self-reported short nighttime sleep duration and daytime sleep of longer than 1 hour were associated with preexisting CVD, breathlessness, depression, poor health, physical inactivity, and manual social class. In all men, self-reported daytime sleep of longer than 1 hour duration was associated with significantly greater risk of HF after adjustment for potential confounders (adjusted hazard ratio (aHR) = 1.69, 95% CI = 1.06-2.71) than in those who reported no daytime napping. Self-reported nighttime sleep duration was not associated with HF risk except in men with preexisting CVD (<6 hours: aHR = 2.91, 95% CI = 1.31-6.45; 6 hours: aHR = 1.89, 95% CI = 0.89-4.03; 8 hours: aHR = 1.29, 95% CI = 0.61-2.71; ≥9 hours: aHR = 1.80, 905% CI = 0.71-4.61 vs nighttime sleep of 7 hours). Snoring was not associated with HF risk.

CONCLUSION

Self-reported daytime napping of longer than 1 hour is associated with greater risk of HF in older men. Self-reported short sleep (<6 hours) in men with CVD is associated with particularly high risk of developing HF.

摘要

目的

研究在有和没有心血管疾病(CVD)的男性中,自我报告的夜间睡眠时间和日间睡眠与心力衰竭(HF)发病之间的关联。

设计

基于人群的前瞻性研究。

地点

英国24个城镇的普通诊所。

参与者

60 - 79岁无HF病史的男性,随访9年(N = 3723)。

测量

从初级保健记录中获取HF发病病例信息。睡眠评估基于自我报告的夜间睡眠时间和日间小睡情况。

结果

自我报告的夜间睡眠时间短以及日间睡眠超过1小时与既往CVD、呼吸急促、抑郁、健康状况差、身体活动少和体力劳动者社会阶层有关。在所有男性中,调整潜在混杂因素后,自我报告的日间睡眠超过1小时与HF风险显著增加相关(调整后风险比[aHR]=1.69,95%可信区间[CI]=1.06 - 2.71),高于未报告日间小睡的男性。自我报告的夜间睡眠时间与HF风险无关,除非是有既往CVD的男性(<6小时:aHR = 2.91,95%CI = 1.31 - 6.45;6小时:aHR = 1.89,95%CI = 0.89 - 4.03;8小时:aHR = 1.29,95%CI = 0.61 - 2.71;≥9小时:aHR = 1.80,905%CI = 0.71 - 4.61,与夜间睡眠7小时相比)。打鼾与HF风险无关。

结论

自我报告的日间小睡超过1小时与老年男性HF风险增加有关。有CVD的男性自我报告的短睡眠(<6小时)与发生HF的特别高风险有关。