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眼动脱敏再处理疗法对叙利亚难民创伤后应激障碍和抑郁症的疗效:一项随机对照试验的结果

The efficacy of eye movement desensitization and reprocessing for post-traumatic stress disorder and depression among Syrian refugees: results of a randomized controlled trial.

作者信息

Acarturk C, Konuk E, Cetinkaya M, Senay I, Sijbrandij M, Gulen B, Cuijpers P

机构信息

Department of Psychology,Istanbul Şehir University,Istanbul,Turkey.

Institute for Behavioral Studies,Istanbul,Turkey.

出版信息

Psychol Med. 2016 Sep;46(12):2583-93. doi: 10.1017/S0033291716001070. Epub 2016 Jun 29.

DOI:10.1017/S0033291716001070
PMID:27353367
Abstract

BACKGROUND

Previous research indicates a high prevalence of post-traumatic stress disorder (PTSD) and depression among refugees. Eye movement desensitization and reprocessing (EMDR) is an effective treatment for PTSD for victims of natural disasters, car accidents or other traumatic events. The current study examined the effect of EMDR on symptoms of PTSD and depression by comparing the treatment with a wait-list control condition in Syrian refugees.

METHOD

Adult refugees located in Kilis Refugee Camp at the Turkish-Syrian border with a PTSD diagnosis were randomly allocated to either EMDR (n = 37) or wait-list control (n = 33) conditions. All participants were assessed with the Mini-International Neuropsychiatric Interview Plus at pre-intervention, at 1 week after finishing the intervention and at 5 weeks after finishing the intervention. The main outcome measures were the Harvard Trauma Questionnaire (HTQ) and the Impact of Event Scale-Revised. The Beck Depression Inventory and the Hopkins Symptoms Checklist-25 were included as secondary outcome measures. The Trial Registration no. is NCT01847742.

RESULTS

Mixed-model analyses adjusted for the baseline scores indicated a significant effect of group at post-treatment indicating that the EMDR therapy group showed a significantly larger reduction of PTSD symptoms as assessed with the HTQ. Similar findings were found on the other outcome measures. There was no effect of time or group × time interaction on any measure, showing that the difference between the groups at the post-treatment was maintained to the 5-week follow-up.

CONCLUSIONS

EMDR may be effective in reducing PTSD and depression symptoms among Syrian refugees with PTSD located in a refugee camp.

摘要

背景

先前的研究表明,难民中创伤后应激障碍(PTSD)和抑郁症的患病率很高。眼动脱敏再处理疗法(EMDR)是治疗自然灾害、车祸或其他创伤事件受害者PTSD的有效方法。本研究通过将该疗法与等待名单对照组进行比较,检验了EMDR对叙利亚难民PTSD和抑郁症状的影响。

方法

位于土耳其-叙利亚边境基利斯难民营的成年PTSD诊断难民被随机分配到EMDR组(n = 37)或等待名单对照组(n = 33)。所有参与者在干预前、干预结束后1周和干预结束后5周接受简易国际神经精神访谈加版评估。主要结局指标为哈佛创伤问卷(HTQ)和事件影响量表修订版。贝克抑郁量表和霍普金斯症状清单-25作为次要结局指标。试验注册号为NCT01847742。

结果

对基线分数进行调整的混合模型分析表明,治疗后组间存在显著效应,表明EMDR治疗组使用HTQ评估的PTSD症状显著减轻。在其他结局指标上也发现了类似的结果。时间或组×时间交互作用对任何指标均无影响,表明治疗后组间差异在5周随访时仍保持。

结论

EMDR可能对难民营中患有PTSD的叙利亚难民减轻PTSD和抑郁症状有效。

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