Wang Xiao-Gang, Dong Jing, Pu Yu-Lan, Liu Hui-Jun, Wu Qiang
Shanxi Eye Hospital, Taiyuan 030002, Shanxi Province, China; Department of Ophthalmology, the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China.
The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China.
Int J Ophthalmol. 2016 Jun 18;9(6):876-80. doi: 10.18240/ijo.2016.06.15. eCollection 2016.
To compare the axial lengths (ALs) measured with Lenstar, IOLMaster and A-scan contact ultrasound (Ultrasound) in normal and high myopia (HM).
Eighty-four normal eyes and 49 HM eyes were included. Three consecutive measurements were performed on each eye in the following order: Lenstar, IOLMaster, and Ultrasound. The repeatabilities of the AL measurements for each instrument were assessed by calculating the pooled coefficients of variation (CVs) of 18 eyes in each group. Comparisons between the HM and normal groups were made with independent sample t-tests. The inter-device agreements were evaluated with Bland-Altman analyses and paired two-tailed t-tests.
For normal group, the CVs of the AL measurements taken with the Lenstar, IOLMaster and Ultrasound were 0.001%, 0.01% and 0.14%, respectively. The corresponding CVs for the HM group were 0.005%, 0.02% and 0.15%, respectively. There was significant difference between the Lenstar and the IOLMaster in normal group (P=0.031) but not in HM group (P=0.100). In the two groups, the Lenstar and the IOLMaster produced higher values than did the Ultrasound (all P<0.001). All three instruments exhibited good agreement in terms of AL values. For the intraocular lens (IOL) power calculation using SRK II formula, the Lenstar and the IOLMaster showed 0.5 D higher than Ultrasound in both groups (all P<0.001). No significant difference existed between the Lenstar and the IOLMaster for the IOL power calculation in both normal (P=0.474) and HM group (P=0.103).
The three devices exhibited excellent intra-visit repeatabilities in the AL measurements. The AL and IOL power difference between partial coherence interferometry and ultrasound instruments should be noticed.
比较Lenstar、IOLMaster和A超接触式超声（超声）测量正常眼和高度近视（HM）眼轴长度（AL）的情况。
纳入84只正常眼和49只HM眼。对每只眼按以下顺序进行连续三次测量：Lenstar、IOLMaster和超声。通过计算每组18只眼的合并变异系数（CV）来评估每种仪器AL测量的重复性。采用独立样本t检验对HM组和正常组进行比较。用Bland-Altman分析和配对双尾t检验评估仪器间的一致性。
正常组中，Lenstar、IOLMaster和超声测量AL的CV分别为0.001%、0.01%和0.14%。HM组相应的CV分别为0.005%、0.02%和0.15%。正常组中Lenstar和IOLMaster之间存在显著差异（P = 0.031），但HM组中无显著差异（P = 0.100）。在两组中，Lenstar和IOLMaster测得的值均高于超声（所有P < 0.001）。所有三种仪器在AL值方面均表现出良好的一致性。对于使用SRK II公式计算人工晶状体（IOL）度数，Lenstar和IOLMaster在两组中均比超声高0.5 D（所有P < 0.001）。在正常组（P = 0.474）和HM组（P = 0.103）中，Lenstar和IOLMaster在IOL度数计算方面无显著差异。
这三种设备在AL测量中表现出优异的单次测量重复性。应注意部分相干干涉测量法和超声仪器在AL及IOL度数上的差异。
