Roychoudhury A, Giri A K
Department of Botany, University of Calcutta, India.
Mutat Res. 1989 Jul;223(3):313-9. doi: 10.1016/0165-1218(89)90125-0.
The effects of 4 permitted food dyes, i.e., fast green FCF, indigo carmine, orange G and tartrazine, and the non-permitted dye metanil yellow on chromosomes of Allium cepa are reported. A significant increase in polyploid cells was observed in all cases. High doses of these dyes induced chromosome breaks and micronucleus formation. Although all dyes produced mitotic aberrations, metanil yellow and fast green FCF showed comparatively stronger clastogenic activity.
报告了4种允许使用的食用色素，即亮绿FCF、靛蓝胭脂红、橙黄G和柠檬黄，以及禁用染料间胺黄对洋葱染色体的影响。在所有情况下均观察到多倍体细胞显著增加。高剂量的这些染料会导致染色体断裂和微核形成。尽管所有染料都会产生有丝分裂畸变，但间胺黄和亮绿FCF表现出相对较强的致断裂活性。
