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基于角光栅-微环谐振器的具有大测量范围的集成无标记光学生化传感器。

Integrated label-free optical biochemical sensor with a large measurement range based on an angular grating-microring resonator.

作者信息

Ma Tao, Sun Lei, Yuan Jinhui, Sang Xinzhu, Yan Binbin, Wang Kuiru, Yu Chongxiu

出版信息

Appl Opt. 2016 Jun 20;55(18):4784-90. doi: 10.1364/AO.55.004784.

Abstract

We propose and design a photonic-integrated optical biochemical sensor, which comprises a microring resonator and angular gratings in a silicon-on-insulator waveguide. With the combination of the angular gratings, the measurement range of the angular grating-microring resonator-based sensor significantly increases without the restriction of a free spectral range. Optimization of the several key structural parameters is investigated to achieve favorable transmission properties. A high-quality factor of more than 1.03×10 can meet the requirements of high sensitivity and low detection limit. The simulation results on the biochemical bulk sensing show that a concentration sensitivity of more than 95.27 pm/% and detection limit of less than 0.329% can be obtained. A large measurement range of 50.2 nm is achieved by the combination of the angular gratings. The investigation on the combination of microring resonator and angular grating is a valuable exploration of the liquid and gas biomedical sensing for the ultra-large measurement range.

摘要

我们提出并设计了一种光子集成光学生化传感器,它由绝缘体上硅波导中的微环谐振器和角光栅组成。通过角光栅的组合,基于角光栅 - 微环谐振器的传感器的测量范围显著增加,而不受自由光谱范围的限制。研究了几个关键结构参数的优化,以实现良好的传输特性。超过1.03×10的高品质因数能够满足高灵敏度和低检测限的要求。生化体传感的模拟结果表明,浓度灵敏度超过95.27 pm/%,检测限小于0.329%。通过角光栅的组合实现了50.2 nm的大测量范围。对微环谐振器和角光栅组合的研究是对超大测量范围的液体和气体生物医学传感的一次有价值的探索。

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