Gerke D C, Crabb G A, Frewin D B, Frost B R
Aust Dent J. 1977 Dec;22(6):423-7. doi: 10.1111/j.1834-7819.1977.tb05144.x.
The adrenaline content of local anaesthetic solutions has been assessed using a bioassay system and a fluorometric assay method. It was found that exposure of the solutions to daylight for a period of six months greatly reduced their adrenaline content, whereas storage of the same solutions under refrigeration or in the dark reduced the decrease in catecholamine content. Solutions containing adrenaline which were shown in the clinical situation to give inadequate anaesthesia were also tested. The analysis revealed a decline of catecholamine content in each solution.
已使用生物测定系统和荧光测定法评估了局部麻醉溶液中的肾上腺素含量。结果发现，将溶液暴露于日光下六个月会大大降低其肾上腺素含量，而将相同溶液冷藏或避光保存则可减少儿茶酚胺含量的下降。还对临床情况下显示麻醉效果不佳的含肾上腺素溶液进行了测试。分析表明每种溶液中的儿茶酚胺含量均有所下降。
