Benabdelaziz Imane, Marcourt Laurence, Benkhaled Mohammed, Wolfender Jean-Luc, Haba Hamada
a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Faculté des Sciences de la Matière, Département de Chimie , Université de Batna-1 , Batna , Algérie.
b Phytochemistry and Bioactive Natural Products, School of Pharmaceutical Science, EPGL , University of Geneva , Geneva , Switzerland.
Nat Prod Res. 2017 Mar;31(6):686-690. doi: 10.1080/14786419.2016.1209669. Epub 2016 Jul 15.
In this study, the various extracts of aerial parts of Helianthemum sessiliflorum Pers. were examined in vitro for possible source of antioxidants and for antibacterial activity. The antioxidant activity was performed by DPPH radical scavenging method which showed that ethyl acetate extract possessed the best antioxidant potential (IC = 32.75 ± 2.07 μg/mL). The significant linear correlation was realised between the values of the total phenolic/flavonoid content and antioxidant activity of plant extracts. The ethyl acetate and n-butanol extracts showed moderate antibacterial activity. In addition, the phytochemical study of n-butanol extract afforded nine known phenolic compounds (1-9). This is the first report of six of them (1, 3, 5-8) in Cistaceae family. The structural identification of the isolated compounds was achieved using several spectroscopic methods.
在本研究中，对半日花（Helianthemum sessiliflorum Pers.）地上部分的各种提取物进行了体外抗氧化剂来源及抗菌活性检测。采用DPPH自由基清除法测定抗氧化活性，结果表明乙酸乙酯提取物具有最佳抗氧化潜力（IC = 32.75 ± 2.07 μg/mL）。植物提取物的总酚/黄酮含量与抗氧化活性之间存在显著线性相关性。乙酸乙酯和正丁醇提取物表现出中等抗菌活性。此外，正丁醇提取物的植物化学研究得到了9种已知酚类化合物（1 - 9）。其中6种化合物（1、3、5 - 8）在半日花科中的报道尚属首次。通过多种光谱方法对分离得到的化合物进行了结构鉴定。
