Sinha Lagnojita, Brankov Jovan G, Tichauer Kenneth M
Opt Lett. 2016 Jul 15;41(14):3225-8. doi: 10.1364/OL.41.003225.
Optical tomography can yield anatomical and molecular information about biological tissue. However, its spatial resolution is poor in thick samples owing to high scatter. Early photon approaches, where photon arrival times are measured with time-resolved detectors, provide one means of improving spatial resolution through selection of photons that travel a straighter path. Here, a novel approach to significantly enhance detection of early photons in time-correlated single photon counting with avalanche photodiodes has been discussed. Results suggest that the early photon detection rate can be increased by about 10 orders of magnitude by running the detector in a dead-time regime.
光学断层扫描可以提供有关生物组织的解剖学和分子信息。然而，由于高散射，其在厚样本中的空间分辨率较差。早期光子方法，即通过时间分辨探测器测量光子到达时间，提供了一种通过选择沿更直路径传播的光子来提高空间分辨率的方法。在此，讨论了一种在雪崩光电二极管的时间相关单光子计数中显著增强早期光子检测的新方法。结果表明，通过在死区时间模式下运行探测器，早期光子检测率可提高约10个数量级。
