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创伤愈合：生物制剂、皮肤替代物、生物膜和支架。

Wound Healing: Biologics, Skin Substitutes, Biomembranes and Scaffolds.

机构信息

Division of Plastic Surgery, Department of Surgery, University of Kentucky, Kentucky Clinic K454, 740 South Limestone, Lexington, KY 40536, USA.

出版信息

Healthcare (Basel). 2014 Sep 10;2(3):356-400. doi: 10.3390/healthcare2030356.

DOI:10.3390/healthcare2030356
PMID:27429283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4934597/
Abstract

This review will explore the latest advancements spanning several facets of wound healing, including biologics, skin substitutes, biomembranes and scaffolds.

摘要

本篇综述将探讨创面愈合多个方面的最新进展，包括生物制剂、皮肤替代物、生物膜和支架。

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本文引用的文献

1
Microbial cellulose wound dressing in the treatment of nonhealing lower extremity ulcers.微生物纤维素伤口敷料治疗下肢难愈合溃疡
Wounds. 2009 Jan;21(1):1-3.
2
Preparation and characterization of double crosslinked hydrogel films from carboxymethylchitosan and carboxymethylcellulose.制备并表征了羧甲基壳聚糖和羧甲基纤维素的双交联水凝胶膜。
Carbohydr Polym. 2014 Sep 22;110:113-20. doi: 10.1016/j.carbpol.2014.03.095. Epub 2014 Apr 6.
3
Green synthesis of a new gelatin-based antimicrobial scaffold for tissue engineering.用于组织工程的新型明胶基抗菌支架的绿色合成
Mater Sci Eng C Mater Biol Appl. 2014 Jun 1;39:235-44. doi: 10.1016/j.msec.2014.03.007. Epub 2014 Mar 12.
4
Preparation and characterization of silver nanoparticles-loaded calcium alginate beads embedded in gelatin scaffolds.负载银纳米颗粒的海藻酸钙珠嵌入明胶支架的制备与表征
AAPS PharmSciTech. 2014 Oct;15(5):1105-15. doi: 10.1208/s12249-014-0140-9. Epub 2014 May 23.
5
An investigation of common crosslinking agents on the stability of electrospun collagen scaffolds.常见交联剂对静电纺丝胶原支架稳定性的研究
J Biomed Mater Res A. 2015 Feb;103(2):762-71. doi: 10.1002/jbm.a.35222. Epub 2014 May 28.
6
Electrospun chitosan/sericin composite nanofibers with antibacterial property as potential wound dressings.具有抗菌性能的壳聚糖/丝胶复合纳米纤维电纺膜，可用作潜在的伤口敷料。
Int J Biol Macromol. 2014 Jul;68:92-7. doi: 10.1016/j.ijbiomac.2014.04.029. Epub 2014 Apr 24.
7
Genipin-crosslinked chitosan/poly-L-lysine gels promote fibroblast adhesion and proliferation.京尼平交联壳聚糖/聚-L-赖氨酸水凝胶促进成纤维细胞黏附和增殖。
Carbohydr Polym. 2014 Aug 8;108:91-8. doi: 10.1016/j.carbpol.2014.03.021. Epub 2014 Mar 21.
8
Genipin-crosslinked gelatin-silk fibroin hydrogels for modulating the behaviour of pluripotent cells.用于调节多能细胞行为的京尼平交联明胶-丝素蛋白水凝胶
J Tissue Eng Regen Med. 2016 Oct;10(10):876-887. doi: 10.1002/term.1868. Epub 2014 Jan 29.
9
Dermagraft: Use in the Treatment of Chronic Wounds.德美皮肤替代物：用于慢性伤口的治疗。
Adv Wound Care (New Rochelle). 2012 Jun;1(3):138-141. doi: 10.1089/wound.2011.0282.
10
Skin substitutes based on allogenic fibroblasts or keratinocytes for chronic wounds not responding to conventional therapy: a retrospective observational study.基于同种异体成纤维细胞或角质形成细胞的皮肤替代物用于对传统治疗无反应的慢性伤口：一项回顾性观察研究。
Int Wound J. 2016 Feb;13(1):44-52. doi: 10.1111/iwj.12223. Epub 2014 Feb 12.