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口服硫酸锌作为威尔逊病患儿的主要治疗干预措施。

Oral zinc sulphate as primary therapeutic intervention in a child with Wilson disease.

作者信息

Milanino R, Marrella M, Moretti U, Velo G P, Deganello A, Ribezzo G, Tatò L

机构信息

Istituto di Farmacologia, University of Verona, Italy.

出版信息

Eur J Pediatr. 1989 Jun;148(7):654-5. doi: 10.1007/BF00441526.

DOI:10.1007/BF00441526
PMID:2744040
Abstract

An 8-year-old boy with an hepatic form of Wilson disease was treated with oral zinc sulphate as the primary and sole therapy. After 4 months, liver function had dramatically improved, and the parameters characterizing copper metabolism had also normalized.

摘要

一名患有肝豆状核变性(Wilson病)的8岁男孩接受了口服硫酸锌治疗,作为主要且唯一的治疗方法。4个月后,肝功能显著改善,且表征铜代谢的各项参数也恢复了正常。

相似文献

1
Oral zinc sulphate as primary therapeutic intervention in a child with Wilson disease.口服硫酸锌作为威尔逊病患儿的主要治疗干预措施。
Eur J Pediatr. 1989 Jun;148(7):654-5. doi: 10.1007/BF00441526.
2
Oral zinc as initial therapy in Wilson's disease: two years of continuous treatment in a 10-year-old child.口服锌作为肝豆状核变性的初始治疗:一名10岁儿童的两年持续治疗
Acta Paediatr. 1992 Feb;81(2):163-6. doi: 10.1111/j.1651-2227.1992.tb12195.x.
3
Effective treatment of Wilson's disease with oral zinc sulphate: two case reports.口服硫酸锌有效治疗威尔逊氏病:两例病例报告。
Br Med J (Clin Res Ed). 1984 Aug 4;289(6440):273-6. doi: 10.1136/bmj.289.6440.273.
4
3 years of continuous oral zinc therapy in 4 patients with Wilson's disease.4例威尔逊病患者接受3年持续口服锌治疗。
Acta Neurol Scand. 1983 Jun;67(6):356-64. doi: 10.1111/j.1600-0404.1983.tb03153.x.
5
Oral zinc sulphate for Wilson's disease.口服硫酸锌治疗威尔逊氏病。
Arch Dis Child. 1985 Jul;60(7):656-9. doi: 10.1136/adc.60.7.656.
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[Oral zinc in Wilson disease--an alternative to D-penicillamine].[口服锌剂治疗肝豆状核变性——D-青霉胺的替代疗法]
Z Gastroenterol. 1985 Jan;23(1):25-9.
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Low-dose zinc therapy for maintenance treatment of Wilson's disease.低剂量锌疗法用于威尔逊病的维持治疗。
Clin Pharm. 1990 Dec;9(12):951-3.
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Oral zinc sulphate as long-term treatment in Wilson's disease (hepatolenticular degeneration).口服硫酸锌用于肝豆状核变性(威尔逊病)的长期治疗。
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Zinc therapy as the initial treatment for Wilson's disease.锌疗法作为威尔逊氏病的初始治疗方法。
Arch Neurol. 1988 Apr;45(4):373-4. doi: 10.1001/archneur.1988.00520280015007.

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Zinc Monotherapy as an Alternative Treatment Option for Decompensated Liver Disease due to Wilson Disease?锌单药治疗能否作为肝豆状核变性所致失代偿性肝病的替代治疗选择?
Case Reports Hepatol. 2020 Jan 14;2020:1275940. doi: 10.1155/2020/1275940. eCollection 2020.
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WILSON'S DISEASE (A report of two cases).威尔逊氏病(两例报告)
Med J Armed Forces India. 1994 Jan;50(1):63-65. doi: 10.1016/S0377-1237(17)31042-0. Epub 2017 Jun 27.
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Case report: concordant traumatic brainstem contusion delayed diagnosis in a young man with Wilson's disease.

本文引用的文献

1
Oral zinc therapy for Wilson's disease.威尔逊氏病的口服锌疗法。
Ann Intern Med. 1983 Sep;99(3):314-9. doi: 10.7326/0003-4819-99-3-314.
2
Effective treatment of Wilson's disease with oral zinc sulphate: two case reports.口服硫酸锌有效治疗威尔逊氏病:两例病例报告。
Br Med J (Clin Res Ed). 1984 Aug 4;289(6440):273-6. doi: 10.1136/bmj.289.6440.273.
3
[Maintenance treatment of Wilson's disease with oral zinc. Apropos of a child treated for 4 years].
Arch Fr Pediatr. 1985 Jun-Jul;42(6):447-9.
病例报告:一名患有威尔逊氏病的年轻男子出现创伤性脑干挫伤延迟诊断
Eur Child Adolesc Psychiatry. 1995 Jan;4(1):46-54. doi: 10.1007/BF01987966.
4
Orthotopic liver transplantation in liver-based metabolic disorders.基于肝脏的代谢紊乱中的原位肝移植
Eur J Pediatr. 1992;151 Suppl 1:S32-8. doi: 10.1007/BF02125800.
4
Oral zinc sulphate for Wilson's disease.口服硫酸锌治疗威尔逊氏病。
Arch Dis Child. 1985 Jul;60(7):656-9. doi: 10.1136/adc.60.7.656.
5
The treatment of Wilson's disease in paediatrics: oral zinc therapy versus penicillamine.儿童威尔逊病的治疗:口服锌疗法与青霉胺对比
Acta Pharmacol Toxicol (Copenh). 1986;59 Suppl 7:514-7. doi: 10.1111/j.1600-0773.1986.tb02815.x.
6
Treatment of Wilson's disease with zinc: III. Prevention of reaccumulation of hepatic copper.锌治疗威尔逊病:III. 预防肝脏铜的再蓄积。
J Lab Clin Med. 1987 May;109(5):526-31.
7
Zinc-copper interaction provides a novel and apparently effective alternative therapy for Wilson's disease.锌铜相互作用为威尔逊氏病提供了一种新颖且明显有效的替代疗法。
J Lab Clin Med. 1987 May;109(5):521-2.
8
The efficacy of oral zinc therapy as an alternative to penicillamine for Wilson's disease.口服锌疗法作为青霉胺替代疗法治疗威尔逊病的疗效。
N Engl J Med. 1988 Feb 4;318(5):322-3. doi: 10.1056/NEJM198802043180514.
9
Oral zinc sulphate as long-term treatment in Wilson's disease (hepatolenticular degeneration).口服硫酸锌用于肝豆状核变性(威尔逊病)的长期治疗。
Eur Neurol. 1979;18(3):205-11. doi: 10.1159/000115077.